Baker Mayfield's shoulder injury is more serious than initially thought, and while he could opt to tough it out, the Cleveland Browns could very well succeed with backup Case Keenum at the helm.

Breaking down the best and worst action from the Week 6 NFL slate, headlined by the Jacksonville Jaguars rookie quarterback Trevor Lawrence.

Use PFF's WR/CB matchup chart to break down five wide receiver-cornerback matchups to target in Week 7 and five to avoid, including Tampa Bay Buccanneers wide receiver Antonio Brown facing off against the Chicago Bears' Kindle Vildor.

Running back D'Ernest Johnson led the Cleveland Browns to a 17-14 victory over quarterback Teddy Bridgewater and the Denver Broncos on Thursday Night Football.

PFF injury analyst Mario Pilato combs through the official injury reports for each Week 7 NFL game and gives updates and analysis for fantasy-relevant players.

Projecting which NFL player has the best chance of winning the 2021 NFL MVP award by predicting who will have the best combination of individual stats and team wins at the end of the season.

Breaking down the DFS strategies and approaches to playing the DraftKings Showdown slate for the Cleveland Browns-Denver Broncos Thursday Night Football matchup.

The Washington Football Team and Denver Broncos were rumored to be interested in Dolphins quarterback Tua Tagovailoa as part of the situation, but both teams are reportedly not in on a deal.

Cleveland Browns quarterback Baker Mayfield has been ruled out of his side's Thursday Night Football clash against the Denver Broncos, the team announced Thursday. Veteran quarterback Case Keenum will start in Mayfield's absence.

The Tampa Bay Buccaneers lost a few steps from 2020, and instead of relying on quarterback Tom Brady to solve it all in the dropback game, the offense found another way to punish defenses.

At 44 years old, Tampa Bay Buccaneers quarterback Tom Brady continues to defy logic while playing at an elite level.

The Tampa Bay Buccaneers' Tom Brady remains in the top spot in PFF's analytical quarterback rankings ahead of Week 6 of the 2021 NFL season. Derek Carr, Kirk Cousins and Carson Wentz were among the biggest movers up the rankings.

The Dallas Cowboys and the Kansas City Chiefs lead the way among NFL offenses through Week 6 of the 2021 NFL season.

New England Patriots quarterback Mac Jones and Arizona Cardinals linebacker Zaven Collins were among the standout rookies in Week 6 of the 2021 NFL season.

The 15 highest-graded rookies through NFL Week 6, including New England Patriots quarterback Mac Jones and Cincinnati Bengals WR Ja'Marr Chase.

Rookie first-rounders Mac Jones, Zaven Collins and Kadarius Toney were among the standouts in Week 6 of the 2021 NFL season.

Being able to live in two offensive worlds is key for success in the modern game, and QB Dak Prescott is taking advantage of more 12 personnel and less 11 personnel in 2021.

Derrick Henry led the Tennesee Titans to a 34-31 victory over Josh Allen and the Buffalo Bills on Monday Night Football.

PFF’s NFL Team of the Week and player awards from Week 6 of the 2021 NFL season. Indianapolis Colts' Carson Wentz leads the way at quarterback after his clinical performance against the hapless Houston Texans, while Dallas Cowboys edge Randy Gregory headlines on defense.