Indianapolis Colts quarterback Andrew Luck is retiring, sending backup Jacoby Brissett into the starting lineup.

It was a game to forget for the Indianapolis Colts, and in more ways than one, as the 27-17 preseason loss to the Chicago Bears was almost entirely overshadowed by the news of Andrew Luck's retirement.

The Seahawks' first-team offense showed well enough in their third preseason game as Seattle ended the regular-season dress rehearsal with a 23-15 win.

Rookie Dakota Allen put forth another impressive performance as the Los Angeles Rams beat the Denver Broncos, 10-6. 

Matt Breida impressed as the 'Niners beat the Chiefs, 27-17. 

The Saints' backup quarterbacks both showed promise in the side's 23-13 victory over the New York Jets.

Tony Pollard continued his promising preseason as the Dallas Cowboys bested the Houston Texans, 34-0.

Dalvin Cook took an outside zone run backside for an 85-yard touchdown in the Minnesota Vikings' 20-9 win over the Arizona Cardinals on Saturday.

Veteran Matt Barkley continued his dominant preseason with another stellar performance, as he completed 12-of-14 passes for 142 yards and a touchdown in the Buffalo Bills' 24-20 win over the Detroit Lions.