NFL same-game parlay opportunities for Week 4 center on favorable passing matchups for the Giants, Buccaneers and Bills. Jameis Winston and Isaiah Likely draw Arizona, while Jalon Daniels faces a Green Bay defense that has struggled to generate pressure. Josh Allen and DJ Moore also offer an intriguing combination against New England’s man-heavy defense.

Fantasy football managers have received limited explosive rushing production from Jeremiyah Love, Jacory Croskey-Merritt and Quinshon Judkins through three weeks. Love has only one run of 10-plus yards, while Croskey-Merritt and Judkins have two apiece. Their PFF Grades and rushing production highlight why big plays have been difficult to find early in the season.

Dynasty fantasy football trades can create opportunities to acquire low-cost players whose value could rise significantly over the next year. Ricky Pearsall, Shedeur Sanders and Chris Bell each carry limited current value because of injuries or difficult situations.

PFF’s data-backed NFL bets for Week 4 identify passing-game opportunities for the Rams and Jets based on coverage tendencies. Matthew Stafford faces an Eagles defense that ranks around league average in perfect coverage, while Los Angeles has consistently forced coverage mistakes. Garrett Wilson draws a Bears defense that plays man coverage at the NFL’s second-highest rate.

The Commanders vs. Colts betting matchup in London features Washington as a 3.5-point underdog despite holding an early efficiency advantage. Indianapolis brings one of the NFL’s most productive rushing attacks against a Commanders defense that ranks third in EPA per rush allowed. PFF’s matchup analysis also identifies pressure and quarterback play as potential areas of value for Washington.

PFF’s NFL anytime touchdown picks highlight Jahmyr Gibbs, David Montgomery and Garrett Wilson based on their matchups and scoring opportunities. Gibbs has scored six touchdowns through three weeks, while Montgomery has handled three of Houston’s four carries inside the 5-yard line.

Cowboys receiver CeeDee Lamb vs. Texans corner Derek Stingley Jr. is among the top NFL player duels that will occur in Week 4.

Jaguars rookie receiver Josh Cameron is among the fringe fantasy football starters worth promoting as flexes in Week 4.

Colts receiver Josh Downs is among the wideouts to start in fantasy football lineups for Week 4 of the NFL season.

The Cleveland Browns' young playmakers shining were among the top fantasy football storylines from the Week 4 edition of Thursday Night Football.

The 2027 NFL Draft class faces a revealing weekend as several top prospects take on tougher competition. Julian Sayin leads Ohio State against an Iowa team loaded with draft talent, while Darian Mensah gets his first major road test at Clemson.

Jeremiah Smith enters the 2027 NFL Draft conversation with elite production and a remarkably complete receiving profile at Ohio State. He leads qualifying FBS receivers since 2024 with 3,171 receiving yards and a 94.9 PFF receiving grade. Smith’s combination of size, separation ability, contested-catch success and reliable hands makes him one of the most accomplished wide receiver prospects in recent memory.

Will Anderson Jr. has opened the 2026 season with elite production as both a pass-rusher and run defender for the Houston Texans. He has earned a 93.0 PFF grade while ranking among the position’s leaders in pressure rate and pass-rush win rate.