PFF’s data-backed NFL bets for Week 4 identify passing-game opportunities for the Rams and Jets based on coverage tendencies. Matthew Stafford faces an Eagles defense that ranks around league average in perfect coverage, while Los Angeles has consistently forced coverage mistakes. Garrett Wilson draws a Bears defense that plays man coverage at the NFL’s second-highest rate.

The Commanders vs. Colts betting matchup in London features Washington as a 3.5-point underdog despite holding an early efficiency advantage. Indianapolis brings one of the NFL’s most productive rushing attacks against a Commanders defense that ranks third in EPA per rush allowed. PFF’s matchup analysis also identifies pressure and quarterback play as potential areas of value for Washington.

PFF’s NFL anytime touchdown picks highlight Jahmyr Gibbs, David Montgomery and Garrett Wilson based on their matchups and scoring opportunities. Gibbs has scored six touchdowns through three weeks, while Montgomery has handled three of Houston’s four carries inside the 5-yard line.

Cowboys receiver CeeDee Lamb vs. Texans corner Derek Stingley Jr. is among the top NFL player duels that will occur in Week 4.

Jaguars rookie receiver Josh Cameron is among the fringe fantasy football starters worth promoting as flexes in Week 4.

Colts receiver Josh Downs is among the wideouts to start in fantasy football lineups for Week 4 of the NFL season.

The Cleveland Browns edged the Pittsburgh Steelers 27–24 in Week 4 on October 1, 2026. Browns outgained the Steelers, 377 total yards to 361.

The Cleveland Browns' young playmakers shining were among the top fantasy football storylines from the Week 4 edition of Thursday Night Football.

The 2027 NFL Draft class faces a revealing weekend as several top prospects take on tougher competition. Julian Sayin leads Ohio State against an Iowa team loaded with draft talent, while Darian Mensah gets his first major road test at Clemson.

Jeremiah Smith enters the 2027 NFL Draft conversation with elite production and a remarkably complete receiving profile at Ohio State. He leads qualifying FBS receivers since 2024 with 3,171 receiving yards and a 94.9 PFF receiving grade. Smith’s combination of size, separation ability, contested-catch success and reliable hands makes him one of the most accomplished wide receiver prospects in recent memory.

Will Anderson Jr. has opened the 2026 season with elite production as both a pass-rusher and run defender for the Houston Texans. He has earned a 93.0 PFF grade while ranking among the position’s leaders in pressure rate and pass-rush win rate.

The NFL Special Teams Report highlights the players making an impact beyond kicking, punting and returning in Week 3. JK Scott delivered the special teams play of the week, while Maema Njongmeta led qualifying kick coverage players with a 93.2 PFF grade.

Carolina Panthers safety Zakee Wheatley leads the NFL rookie rankings after Week 3 with an 86.1 PFF grade. Mansoor Delane and Genesis Smith round out the top three, while Josiah Trotter and Max Iheanachor complete the top five.

Max Chadwick and Dalton Wasserman analyze the five best games on the Week 5 college football slate, including Alabama facing Mississippi State.

The Cincinnati Bengals are a rushing operation that could thrive in Week 4, facing off against the Jacksonville Jaguars' defense.

The New Orleans Saints and Carolina Panthers are two NFL offenses that could experience big gains through the air in Week 4.

The San Francisco 49ers' dynamic, efficient offense is one that continues to produce strong results for fantasy football managers entering Week 4.

Chargers running back Omarion Hampton still warrants starting in Week 4 fantasy lineups, while Falcons tight end Kyle Pitts is among the disappointing stars to bench.