Using premium fantasy draft capital on a running back who has had premium real life draft capital invested into them can get huge returns right out of the gate — as those selected in the top 10 since 2015 illustrate. Where it gets dicey is when looking at those backs picked toward the tail end of the first round, and when it comes time for backs to reup.

Below are 10 head-to-head collisions to circle as you determine which games to prioritize watching and/or following this weekend, including Amon-Ra St. Brown vs. Cooper DeJean.

Ja'Marr Chase and Brock Bowers profile as players whose target volume should rebound in Week 11 based on their route usage, quarterback tendencies and predicted target share.

Using route-level PFF data and the Predicted Targets Model, these players could be in line for large fantasy performances in Week 11.

Justin Jefferson draws a highly favorable matchup against a struggling Chicago secondary, making his 69.5-yard receiving line appealing given his consistent target volume. Josh Jacobs also profiles well to clear 78.5 rushing yards as Green Bay leans on him against a Giants defense that ranks near the bottom of the league in run-defense grade.

Max Chadwick pinpoints who he expects to take over at LSU, Penn State, Florida and more.

The race for the Heisman Trophy is heating up with only a few weeks left. Here are Max Chadwick's current Heisman rankings going into Week 12.

Jon Macri provides all the red zone information fantasy football managers need to make informed decisions ahead of Week 11.

Drake Maye delivered another efficient performance and TreVeyon Henderson scored three touchdowns as the New England Patriots pulled away from the New York Jets for a 27-14 win on Thursday night.

PFF's fantasy football recap focuses on player usage and stats, breaking down all the vital information you need to achieve fantasy success in 2025.

At PFF, the run game matters just as much as the pass game, and every play is meticulously graded. Each week, we’ll be looking at the highest-graded run blockers and run defenders from each position.

This article breaks down the factors that drive line movement in betting markets and helps you judge whether a shift is an overreaction or a justified adjustment. Injuries, weather and public pick releases are just a few of the forces that can swing numbers.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 11 contest.

We're diving into the top wide receivers by PFF receiving grade through Week 10 of the 2025 NFL season. To qualify, players need to have played at least 100 receiving snaps. For even more information, including snap counts, receiving by depth, per-route data and more, subscribe to PFF+.

Michelle Magdziuk provides the top running back takeaways from Week 10 that could have a significant impact on fantasy football points in Week 11 and beyond.

The Browns retain the top spot in the PFF defensive line rankings ahead of Week 11, though the Broncos and Eagles have jumped four spots after Week 10.

D.K. Metcalf is coming off two quiet weeks, but he’s in a good position to rebound against Pittsburgh. Bo Nix, meanwhile, should stay on fantasy benches after a rough Thursday night outing and with a matchup against a Kansas City defense that has been excellent at preventing passing touchdowns.

With over half of their sophomore seasons in the rear view mirror, here are five defensive players who have taken significant jumps in their second year.