The Los Angeles Chargers dominated the Indianapolis Colts 20-3 on Monday Night Football.

San Francisco 49ers tight end George Kittle and Philadelphia Eagles wide receiver DeVonta Smith were among the standouts from Week 16 NFL action on Sunday.

PFF broke down the numbers immediately after every NFL Week 16 game, including scores, rookie standouts, offensive line performances and more.

It wasn't pretty, but the Tampa Buccaneers dug deep to beat the Arizona Cardinals 19-16 in Week 16. 

Baker Mayfield and the Los Angeles Rams made short work of the struggling Denver Broncos in Week 16, beating them 51-14.

The Green Bay Packers intercepted Miami Dolphins QB Tua Tagovailoa three times in the second half of this Christmas Day contest, helping Aaron Rodgers & Co. to a 26-20 victory.

The Dallas Cowboys were down for most of the game but were able to make enough plays when it counted to come away with the 40-34 victory on Saturday.

The San Francisco 49ers took down the Washington Commanders 37-20 on Saturday.

The Kansas City Chiefs marched on with an efficient 24-10 win over the Seattle Seahawks, keeping pace with the Buffalo Bills at 12-3 on the year so far.

The Houston Texans defeated the Tennessee Titans in a divisional bout by a score of 19-14. The results brings Houston’s record to 2-12-1 on the year, while the Titans drop to 7-8.

It looked like the Cincinnati Bengals were going to cover as three-point favorites with ease, but the New England Patriots made things interesting late in a 22-18 loss to Cincinnati.

The porous Detroit Lions defense we saw early this season reared its ugly head once again. They had no answer for the Carolina Panthers' rushing attack, which finished with 320 rushing yards on the day en route to a 37-23 win.

It was tough going for a while, but the Buffalo Bills pulled away late and secured a 35-13 win over the Chicago Bears on the road.

The Baltimore Ravens survived a late fight by the Atlanta Falcons to come away with a 17-9 win in Week 16.

In the coldest game in Cleveland Browns history, the team's offense was unsurprisingly still ice cold. They jumped out to an early 10-point lead before salting it away to 17 unanswered points from the New Orleans Saints.

In a Week 16 game with plenty of playoff implications for both sides, the Minnesota Vikings defeated the New York Giants by a score of 27-24.

Quarterback Brock Purdy, Mr. Irrelevant from the 2022 NFL Draft, has stepped into the fray, won his first three games of meaningful action and now has people asking whether he can win a Super Bowl for the San Francisco 49ers.