Trevor Lawrence threw three touchdown passes to set the Jaguars’ single-season scoring record as Jacksonville clinched the AFC South and a home playoff game with a 41-7 rout of Tennessee. The win capped a dominant division run for the Jaguars, while the Titans were overwhelmed and lost rookie quarterback Cam Ward to a shoulder injury early.

PFF’s media research team has been hard at work this week, preparing for kickoff by pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 18 contest.

We get playoff football a little early in Pittsburgh, with this matchup the only true win-and-in game of the weekend. 

With 256 games already in the books from Weeks 1 through 17, the sheer volume of plays this season provides a robust sample size for meaningful trends to emerge. In this article, we’ll dive into five of the most interesting statistical stories that data has revealed.

Seattle locked up the NFC’s No. 1 seed and the NFC West title by stifling San Francisco’s high-powered offense in a 13-3 win, leaning on a dominant defense and a balanced run game. The loss sends the 49ers on the road for the wild-card round after their lowest-scoring and lowest-yardage outing under Kyle Shanahan.

Baker Mayfield threw a touchdown to Cade Otton and Chase McLaughlin kicked three field goals as the Buccaneers stayed alive with a sloppy 16-14 win over the Panthers in rainy Tampa. Tampa Bay now needs New Orleans to beat or tie Atlanta to clinch the NFC South, while Carolina can still win the division if the Falcons prevail.

Below are 10 head-to-head collisions to circle as you determine which games to prioritize watching and/or following this weekend, including Alex Highsmith vs. Ronnie Stanley.

The Browns boast the NFL’s best defensive line in 2025, anchored by Defensive Player of the Year favorite Myles Garrett, who leads the league with a 92.7 overall grade while ranking among the top edge defenders against both the run and the pass. Even after losing Maliek Collins to injury, Cleveland’s depth — highlighted by Alex Wright, Isaiah McGuire and a surging rookie Mason Graham — has kept the unit dominant from top to bottom.

Cooper DeJean continues to separate himself at the top of the coverage metrics, pairing a league-leading advanced coverage grade with elite playmaking production, including 18 pass stops and 12 forced incompletions. Meanwhile, Jamel Dean remains the model of consistency, allowing a catch on just 45.5% of targets with a 46.9 passer rating allowed.

PFF is grading every player on every play during the 2025 NFL season, and these are the top wide receivers by PFF receiving grade through 17 weeks.

Every New Year brings the familiar tradition of setting resolutions — going to the gym more consistently, reading more books or simply committing to self-improvement in the year ahead. With that in mind, what would it look like if each NFL team set its own New Year’s resolution for 2026?

We're diving into every matchup in Week 18 of the 2025 NFL season — including key storylines, matchups to watch and injury news. The Carolina Panthers and Tampa Bay Buccaneers kick things off on Saturday night.

Jeffery Simmons extended his lead at the top of the interior defender leaderboard, while Panthers rookie Nic Scourton put together his best showing yet.

The Eagles' and Titans' offensive lines continue to climb as the 2025 NFL regular season winds down.

In this quarterback rankings breakdown, we've evaluated the top performers based on PFF passing grades. Using insights from Premium Stats, we’ll also present a variety of key grades beyond passing grade, including grades under pressure, from a clean pocket, against the blitz and more.

The power rankings below provide clear tiers on each NFL team's market assessment, offering a comprehensive view of team standings and future prospects. All of the information below and more can be found in PFF’s power rankings tool, which is available with a PFF+ subscription.

The Panthers-Buccaneers Week 18 game for the division could become meaningless amid a three-way tie atop the NFC South, a scenario in which the Panthers would clinch.

We'll examine team performance in various categories after each week of the 2025 NFL season.