NFL Week 6: Schedule, odds and best early bets

• Bet Bills QB Josh Allen — Over 2.5 pass TDs (+161): After nearly 80 combined points and 1,000 total yards in the January instant classic, fun play with a huge Greenline edge (18.8%).

• Bet Jaguars RB Travis Etienne — Under 32.5 rush yards (-105): Game-high PFF Greenline edge of 6.3%.

• Bet Giants RB Saquon Barkley — Over 18.5 carries (+109): 5.4% PFF Greenline edge.

• New users who bet $10 or more at BetMGM will receive a free year’s subscription to PFF+ — a $79.99 value.

Last updated: Sun. Oct. 16, 10:00 a.m.

Estimated reading time: 2 mins

Take a look at the odds for every Week 6 game, courtesy of BetMGM, followed by PFF Greenline and PFF staff best bets.

Sunday, Oct. 16

Tampa Bay Buccaneers @ Pittsburgh Steelers

• Bet QB Kenny Pickett u36.5 pass attempts (-116): Currently PFW Greenline's greatest edge of Week 6 — 39.7%.

• Bet WR Mike Evans o24.5 yards longest completion (-108): Steelers have allowed league-high 30 catches of 15+ yards; Evans has gone over this total in past 4 games.

Cincinnati Bengals @ New Orleans Saints

• Bet Bengals WR JaMarr Chase o6.5 receptions (+102): 7% PFF Greenline Edge.

• Bet Bengals QB Joe Burrow u0.5 INT (-119): Only one turnover-worthy play in past 72 drop backs.

Jacksonville Jaguars @ Indianapolis Colts

• Bet Jaguars RB Travis Ettiene — Under 32.5 rush yards (-105): Game-high PFF Greenline edge of 6.3%.

• Bet Matt Ryan — Under 1.5 pass TDs vs. Jaguars (-130): Ryan is dead last in EPA/play when the defense plays a coverage where middle of the field is open (MOFO), which Jags do at NFL's sixth-highest rate.

New England Patriots @ Cleveland Browns

• Bet Patriots +2.5: Browns are 29th in EPA/play allowed defensively, while New England is 8th and appears equipped to stop fairly limited passing game.

• Bet Browns RB Nick Chubb o18.5 yards longest carry (-110): Chubb over this mark in past 10 games spanning to 2021 season.

New York Jets @ Green Bay Packers

• Bet Jets RB Michael Carter — Under 7.5 carries (-102): Game-high 24.5% PFF Greenline edge.

Baltimore Ravens @ New York Giants

• Bet RB Saquon Barkley — Over 18.5 carries (+109): 5.4% PFF Greenline edge.

• Bet Ravens -6 at Giants: Toughest game of the season for Giants, and it’s doubtful they have the offense capable of keeping pace with the Ravens (8th in EPA/play, 6th in PFF pass-blocking).

Minnesota Vikings @ Miami Dolphins

Bet WR K.J. Osborn — Under 2.5 receptions (+100): Game-high PFF Greenline edge of 14%.

San Francisco 49ers @ Atlanta Falcons

Bet TE George Kittle — Under 3.5 receptions (+111): PFF Greenline edge of 11.6%.

Bet RB Jeff Wilson Jr. — Over 8.5 receiving yards (-110): At least one back has went over this mark against Atlanta, which has allowed the ninth-most total yards to the position.

Carolina Panthers @ Los Angeles Rams

Bet Rams WR Cooper Kupp — Over 7.5 receptions (-145): 11.8% PFF Greenline edge.

Arizona Cardinals @ Seattle Seahawks

• Bet WR Tyler Lockett — Over 5.5 catches (+120): PFF Greenline edge of 7.5%.

Buffalo Bills @ Kansas City Chiefs

• Bet QB Josh Allen — Over 2.5 pass TDs (+161): After nearly 80 combined points and 1,000 total yards in the January instant classic, fun play with a huge Greenline edge (18.8%).

• Bet RB Clyde Edwards-Helaire — Under 2.5 receptions (+128): Game-high PFF Greenline edge of 26.6%.

Dallas Cowboys @ Philadelphia Eagles

Bet Cowboys +6.5: PFF Greenline edge of 1.7%.

Monday, Oct. 17

Denver Broncos @ Los Angeles Chargers

Bet Broncos ml: PFF Greenline edge of 3.4%.

Bet Broncos +4.5: Denver's defense is keeping games close — and the Chargers struggle to put teams away.