• Deebo Samuel and Kliff Kingsbury are the perfect pairing: Kingsbury found some success with Rondale Moore and Greg Dortch with the Arizona Cardinals. Samuel can take that role to an entirely new level.

• Samuel’s injuries have been a problem: The versatile wideout has dealt with multiple injuries in most seasons of his career, costing him playing time and hurting his quality of play in several games.

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Estimated Reading Time: 9 minutes

PFF’s Fantasy Football Player Profile series delivers the most in-depth fantasy football analysis available for the 2025 season.

Using PFF’s exclusive data, we evaluate player performance, competition for touches and how teammates and coaching staffs will impact each player's fantasy football outlook.

Last updated: 7:15 a.m. Monday, May 26

Player Performance

The 49ers made Samuel a second-rounder in 2019. After his solid rookie season, his 2020 campaign was hampered by injuries, with a foot fracture, a hamstring strain and another hamstring strain costing him three games each. 

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