Premium Content Sign Up

2022 Wild-Card Playoffs NFL Odds and Best Bets

Paradise, Nevada, USA; Las Vegas Raiders quarterback Derek Carr (4) celebrates with quarterback Marcus Mariota (8) during the second half against the Los Angeles Chargers at Allegiant Stadium. Mandatory Credit: Orlando Ramirez-USA TODAY Sports

Odds for the wild-card round of the 2022 NFL playoffs are live, and we’ve tried to identify early spreads to bet now before the slew of money comes in and beats the end-of-week spreads into place. Last week, we went 1-1 on our picks, getting closing line value on both. However, our pick of the week on the PFF Forecast lost (IND -15.5) and didn’t even get closing line value (it closed IND -14, and IND lost outright). We move on to the postseason.

Related content for you:

Why betting early is critical to beating NFL markets via Robert Greer

Make sure you check PFF’s betting dashboards when our weekly model predictions go live on Tuesdays, and of course, monitor the Best Bets and Player Props tools to find the very best betting value as college football bowl season and the NFL regular season wind down. Both the NFL and NCAA betting dashboards are plus-30 or more units on the season against early lines and are positive against closing lines as well.

Click here for more PFF tools:

Rankings & Projections | WR/CB Matchup Chart | NFL & NCAA Betting Dashboards | NFL Player Props tool | NFL & NCAA Power Rankings
Best Bets Tool

Wild-Card Round NFL Football Betting Odds (spread, total)

Find all current spreads and PFF’s model predictions on our NFL scores page

Bye: Tennessee Titans, Green Bay Packers


(5) Las Vegas Raiders @ (4) Cincinnati Bengals (-6.5, 49) | 4:35pm ET
(6) New England Patriots @ (3) Buffalo Bills (-4.5, 43.5) | 8:15pm ET


(7) Philadelphia Eagles @ (2) Tampa Bay Buccaneers (-9, 49) | 1:05pm ET
(6) San Francisco 49ers @ (3) Dallas Cowboys (-3, 49.5) | 4:40pm ET
(7) Pittsburgh Steelers @ (2) Kansas City Chiefs (-13, 46.5) | 8:15pm ET


(5) Arizona Cardinals @ (4) Los Angeles Rams (-4.5, 50.5) | 8:15pm ET

Wild-Card Round Best Early NFL Bets

Teaser legs:

None available right now. Watch for:

  • Buccaneers to get to -8.5 for a tease to -2.5
  • 49ers to get to +2.5 for a tease to +8.5


Unlimited Fantasy League Sync
Fantasy Start/Sit Line-Up Optimizer & Waiver Wire
WR-CB & OL-DL Matchups, PFF Player Grades, & Premium Stats 2.0 Tools
Nathan Jahnkes Rankings - #1 Most Accurate Last 70 Weeks
PFF Best Bets, Player Props, & Power Ranking Tools
NFL Mock Draft Sim with Trades & Draft Grades

Already have a subscription? Log In

Betting Featured Tools
  • PFF's Best Bets Tool reveals the bets PFF's data and algorithms give the biggest edge to within spread, total, player prop, and moneyline markets.

    Available with

  • PFF's Player Props Tool reveals betting opportunities within player prop markets.

    Available with

  • Power Rankings are PFF’s NFL power ratings based on weekly player grades in each facet of play. These power rankings are adjusted based on coach, quarterback and the market each season.

    Available with

  • PFF predictions and real time spread, moneyline and over/under lines for each NFL game.

    Available with

  • PFF predictions and real time spread, moneyline and over/under lines for each NCAA game.

    Available with


Unlock the 2023 Fantasy Draft Kit, with League Sync, Live Draft Assistant, PFF Grades & Data Platform that powers all 32 Pro Teams

$31 Draft Kit Fee + $8.99/mo
$89.88/yr + FREE Draft Kit