The New Orleans Saints downgrade cornerback Marshon Lattimore to questionable Saturday, and there's a chance he may miss the Saints' Week 1 game vs. Packers

The Indianapolis Colts will have two key starters back Week 1, as quarterback Carson Wentz and left guard Quenton Nelson will play against the Philadelphia Eagles Sunday.

The Kansas City Chiefs activated star defensive back Tyrann Mathieu from the COVID-19 list Saturday.

As the season nears its beginning, the Eagles agree to a long-term deal with hidden gem left tackle Jordan Mailata.

The Detroit Lions placed left tackle Taylor Decker on injured reserve Saturday, and he will likely be replaced by rookie Penei Sewell, who slides over from right tackle.

Los Angeles Chargers running back Austin Ekeler is expected to play Sunday against the Washington Football Team despite practicing just one day this week with a limited designation.

PFF analysts Andrew Erickson and Ben Brown make their PrizePicks for Week 1 of the 2021 NFL Season.

Here you can find everything from Week 1 injury reports to skill position rankings to potential DFS blowup candidates. So sit back, relax and let PFF's team of analysts guide you to that Week 1 win.

Your home for all of PFF's betting content ahead of Week 1 of the NFL season and Week 2 of the college football season.

Chicago Bears QB Justin Fields should be the NFL's best rookie QB this season, and this PFF data study reveals why.

The weekend slate of Week 1 NFL games is already underway, and among the last-minute value bets is Cincinnati Bengals QB Joe Burrow over 7.5 rushing yards.

The 2021 NFL season is here, which means it's time to set our fantasy football lineups and optimize scoring outputs based on matchups and implied point totals.

The Indianapolis Colts locked in Nyheim Hines with a three-year extension Friday.

Dallas Cowboys right tackle La'el Collins was suspended for five games Friday.

Dallas Cowboys wide receiver Michael Gallup suffered calf strain vs. Buccaneers and is expected to miss three to five weeks.

Curtis Samuel signed a three-year deal with the Washington Football Team this offseason, and he is now set to miss at least the first three weeks of the 2021 NFL season.

Dak Prescott made his long-awaited return from a gruesome ankle injury, and the Dallas Cowboys clearly trusted him to put the team on his back.

Breaking down the top smash, upgrade and fade plays for Week 1 in fantasy football by integrating NFL totals, spreads, implied points and proprietary PFF matchup data.