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NFL Week 10 Fantasy Football Waiver Wire Targets: All league sizes & scoring types

Orchard Park, New York, USA; Buffalo Bills running back Devin Singletary (26) runs with the ball against the Los Angeles Chargers during the fourth quarter at Bills Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

With Week 10 of the fantasy football season on the horizon, it's time to identify the best waiver wire pickups who can help us deal with injuries and bye weeks, setting up managers for a run at the fantasy playoffs.

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The likes of Zack Moss, Chase Edmonds, James Robinson, Kyler Murray, Corey Davis, DeAndre Hopkins, Devontae Booker, Rhamondre Stevenson, Damien Harris and Darrell Henderson are dealing with injuries that could cost significant time in some cases.

Four teams have byes in Week 9. The Chicago Bears, New York Giants, Cincinnati Bengals and Houston Texans will all be taking time off, so key pieces like Joe Mixon and Brandin Cooks will need to be replaced.

For those thinking ahead, the Los Angeles Rams and Denver Broncos are off in Week 11, so adjust waivers accordingly.

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