Baker Mayfield threw for 89 yards and two touchdowns to finish his offseason on a high and put his Carolina Panthers out of sight of the Buffalo Bills.
In the end, the Panthers beat the Bills 21-0 in a result that never really looked in doubt.

Offensive player spotlight: Mayfield went 5-of-9 for 48 yards and two touchdowns from a clean pocket. He threw 6.9 yards down the field on average and short of the sticks on 60% of his attempts.
Defensive player spotlight: Panthers LB Frankie Luvu racked up four defensive stops against the run and two hurries as a blitzer.
Rookie player spotlight: Panthers guard Cade Mays kept a completely clean slate in pass protection on first review. He didn't allow a single pressure across 15 snaps.
Early offensive line analysis: The Bills offensive line was far from great tonight, giving up two sacks and 10 hurries across 30 snaps. It could have gone worse, too: They also combined for a further 10 losses that didn't end up as pressure.
Betting Summary
| Betting Odds | Closing | Result |
| Spread |
CAR -5.5
|
CAR Covers
|
| O/U | 41 |
Under
|
Box Score
Passing
| Buffalo Bills | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Matt Barkley | 4.0 | 9/13 | 100 | 7.7 | 0 | 0 |
| Case Keenum | 0.9 | 8/13 | 46 | 3.5 | 0 | 1 |
| Carolina Panthers | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Baker Mayfield | 12.0 | 9/15 | 89 | 5.9 | 2 | 0 |
| Sam Darnold | 8.1 | 5/11 | 49 | 4.5 | 0 | 0 |
| PJ Walker | 2.0 | 8/10 | 50 | 5.0 | 0 | 0 |
Rushing
| Buffalo Bills | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Raheem Blackshear | 7.9 | 13 | 47 | 3.6 | 0 | 12 |
| Matt Barkley | 4.0 | 1 | 0 | 0.0 | 0 | 0 |
| Duke Johnson | 3.2 | 6 | 20 | 3.3 | 0 | 10 |
| James Cook | 2.3 | 3 | 13 | 4.3 | 0 | 9 |
| Case Keenum | 0.9 | 2 | 1 | 0.5 | 0 | 2 |
| Carolina Panthers | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Baker Mayfield | 12.0 | 1 | 4 | 4.0 | 0 | 4 |
| John Lovett | 11.1 | 14 | 35 | 2.5 | 0 | 7 |
| D'Onta Foreman | 9.6 | 3 | 6 | 2.0 | 0 | 5 |
| Sam Darnold | 8.1 | 2 | 1 | 0.5 | 1 | 1 |
| Chuba Hubbard | 5.9 | 4 | 4 | 1.0 | 0 | 7 |
| Giovanni Ricci | 1.8 | 1 | 0 | 0.0 | 0 | 0 |
Receiving
| Buffalo Bills | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Neil Pau'u | 8.6 | 5 | 4 | 46 | 9.2 | 0 |
| Raheem Blackshear | 7.9 | 2 | 2 | 12 | 6.0 | 0 |
| Isaiah Hodgins | 5.9 | 6 | 4 | 19 | 3.2 | 0 |
| Tommy Sweeney | 5.6 | 2 | 2 | 36 | 18.0 | 0 |
| Duke Johnson | 3.2 | 2 | 1 | 2 | 1.0 | 0 |
| Jake Kumerow | 2.4 | 3 | 1 | 14 | 4.7 | 0 |
| James Cook | 2.3 | 1 | 1 | 0 | 0.0 | 0 |
| Quintin Morris | 2.2 | 3 | 1 | 12 | 4.0 | 0 |
| Tanner Gentry | 1.5 | 2 | 1 | 5 | 2.5 | 0 |
| Carolina Panthers | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Shi Smith | 12.2 | 4 | 3 | 32 | 8.0 | 1 |
| John Lovett | 11.1 | 4 | 4 | 36 | 9.0 | 0 |
| D'Onta Foreman | 9.6 | 2 | 2 | 10 | 5.0 | 1 |
| Chuba Hubbard | 5.9 | 6 | 3 | 25 | 4.2 | 0 |
| Tommy Tremble | 5.3 | 4 | 3 | 23 | 5.8 | 0 |
| Charleston Rambo | 4.1 | 3 | 2 | 21 | 7.0 | 0 |
| Stephen Sullivan | 3.1 | 1 | 1 | 21 | 21.0 | 0 |
| Giovanni Ricci | 1.8 | 1 | 1 | 8 | 8.0 | 0 |
| Derek Wright | 1.6 | 1 | 1 | 6 | 6.0 | 0 |
| Ra'Shaun Henry | 1.3 | 2 | 1 | 3 | 1.5 | 0 |
| Josh Babicz | 1.3 | 1 | 1 | 3 | 3.0 | 0 |
| Rashard Higgins | 0.0 | 1 | 0 | 0 | 0.0 | 0 |
| Terrace Marshall Jr. | 0.0 | 1 | 0 | 0 | 0.0 | 0 |