The Bills fought back in the fourth quarter from a 13-0 deficit, but a wayward Josh Allen throw on a two-point try sealed their fate and ended their AFC East title hopes.

The Giants won the battle between top contenders for the 2026 NFL Draft's No. 1 overall pick in convincing fashion.

The Buccaneers fell 20-17 to the Dolphins, turning the ball over three times and failing to recover an onside kick after a late touchdown, but Carolina’s loss kept Tampa Bay alive in the NFC South race. At 7-9, the Bucs now head into a winner-take-all Week 18 matchup against the Panthers at home with the division title still within reach.

Trevor Lawrence ran for two touchdowns and Cam Little’s go-ahead 42-yard field goal lifted the Jaguars to a 23-17 win over the Colts, extending Jacksonville’s winning streak to seven and putting them one win away from the AFC South title. The loss eliminated Indianapolis from playoff contention, capped a historic collapse after a 7-1 start, and kept Philip Rivers winless since his return.

Shedeur Sanders threw for 186 yards and a touchdown as Cleveland’s defense shut out Pittsburgh in the end zone, lifting the Browns to a 13-6 win that denied the Steelers an AFC North clincher.

Joe Burrow and the Bengals rolled past the Cardinals 37-14, dominating both halves with long, methodical drives as Ja’Marr Chase found the end zone twice and Chase Brown powered in two second-half rushing touchdowns. Arizona showed little resistance outside of late stat-padding from Trey McBride, as Cincinnati controlled the game throughout and cruised to a comfortable home win.

Seattle’s defense shut down Carolina with a dominant performance, holding the Panthers to just 139 total yards and one conversion on 11 third downs in a 27-10 Seahawks win that stalled Carolina’s NFC South push.

Rookie quarterback Tyler Shough has flipped the Saints' fortunes to close out the season, securing his fourth straight win at the helm.

The Patriots inched one step closer to clinching the AFC East title, pending the results of the Bills-Eagles game.

If George Kittle is out, expect the 49ers' passing offense to flow through running back Christian McCaffrey.

Whether you're a seasoned bettor or just getting into the swing of things, the PFF Player Prop Tool gives you actionable takes to beat the sportsbooks.

The Raiders, Dolphins and Jaguars all profile as strong passing-game targets this week. Las Vegas draws a Giants defense bleeding explosive plays, Miami faces a Buccaneers unit that continues to funnel and struggle against the pass, and Jacksonville gets a Colts secondary that has been one of the league’s weakest at producing perfect coverage. Each matchup creates clear paths to ceiling outcomes, making all three spots attractive to attack.

Over the years, PFF data scientists have conducted extensive studies to better understand and predict player performance. While many of these foundational works continue to shape discussions and influence analysis, the focus here is on identifying how those insights apply to specific weekly matchups and uncovering opportunities the betting market may have overlooked.

Anytime touchdown bets are always a fan favorite — but instead of guessing, you can lean on the new PFF Player Prop Tool to separate signal from noise.

The Saints defense has quietly emerged as one of the NFL’s most dominant units, and the market has been slow to catch up. With New Orleans ramping up its blitz rate and Cam Ward struggling both under pressure and in obvious passing situations, the matchup sets up as a difficult one for a Titans offense likely forced to chase points.

Derrick Henry powered the Ravens’ playoff push with a historic night at Lambeau Field, rushing for a season-high 216 yards and four touchdowns in a 41-24 win over the Packers, the most rushing yards ever by a visiting player there. Baltimore dominated on the ground to keep its postseason hopes alive, while Green Bay’s third straight loss helped Chicago clinch the NFC North despite the Packers not punting for a second consecutive game.

The Jacksonville Jaguars are the hottest team in the NFL in late December, a statement few football fans would have expected to be true at the start of the season. And that's because Jaguars quarterback Trevor Lawrence is in the midst of the best stretch of his career.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you.