It was a blowout in the desert, as the Carolina Panthers went into Arizona and handed the Cardinals an embarrassing 34-10 loss. PJ Walker started for the Panthers at quarterback, but Cam Newton came in to score a rushing and passing touchdown.

Woeful performances from both the Pittsburgh Steelers and Detroit Lions led to a tie in Week 10, with Mason Rudolph and Jared Goff failing to jumpstart any semblance of successful offensive attacks.

The New England Patriots crushed the Cleveland Browns in Foxborough, 45-7, stepping forward into contention in the AFC.

Tom Brady threw two first-quarter interceptions, setting the stage for the Washington Football Team to pull off a major upset win over the Tampa Bay Buccaneers in Week 10.

Ryan Tannehill and the Tennessee Titans took down Trevor Siemian and the New Orleans Saints Sunday in a 23-21 slugfest.

The Buffalo Bills went into MetLife Stadium and pounded the New York Jets 45-17 in Week 10 of the 2021 NFL season.

The Indianapolis Colts held on to beat the Jacksonville Jaguars, aided by a late strip-sack of rookie Trevor Lawrence, to move to 5-5 on the 2021 NFL season.

These two NFC teams were heading in opposite directions going into this game, but the Dallas Cowboys righted the ship in a big way by defeating the Atlanta Falcons 43-3 in Week 10.

Former NFL free safety Darius Butler offers his insight into the Week 10 slate and gives his favorite betting picks of the week.

The best Sunday Night single-game and player props for Week 10 are here and feature expected production from Kansas City Chiefs' Tyreek Hill.

The best Week 10 player props are here and feature Tampa Bay Buccaneers QB Tom Brady going over his touchdown passes prop.

Los Angeles Rams wide receiver Robert Woods tore his ACL in practice Friday and will miss the remainder of the season.

Breaking down the best NFL player prop bets to target in Week 10, including a Detroit Lions running back D'Andre Swift carries prop.

PFF injury analyst Mario Pilato combs through the official injury reports for each Week 10 NFL game and gives updates and analysis for fantasy-relevant players.

PFF takes an early look at which positions every team should look to improve upon this offseason.

Doug Kyed dives into his Week 10 mailbag to answer the readers' biggest questions, which include Cam Newton returning to Carolina, Odell Beckham Jr.'s fit with the Rams and Josh Palmer's productivity as a rookie receiver.

Breaking down the best and worst offensive trends from the Week 9 NFL slate, headlined by the Indianapolis Colts' explosive running game versus the New York Jets.

Quarterback Tua Tagovailoa led the Miami Dolphins to a 22-10 victory over quarterback Lamar Jackson and the Baltimore Ravens.