In a game where both teams rested most of its starters, the Tennessee Titans came away with a dominant 34-3 victory over the Tampa Bay Buccaneers.

Second-year Dolphins quarterback Tua Tagovailoa looked comfortable in his preseason Week 2 action against the Atlanta Falcons, and Myles Gaskin was the clear lead back for Miami.

In a game where most of the Seattle Seahawks' starters were resting, the Denver Broncos easily bested them 30-3.

Rookie quarterback Zach Wilson shined in limited action against the Green Bay Packers, further building up the hype around him ahead of the 2021 NFL season.

Mitchell Trubisky got some revenge against his former team on Saturday, leading the Buffalo Bills to four consecutive touchdown drives to open up the game en route to a 41-15 win over the Chicago Bears that was never in question.

Both starting offenses looked sluggish but the Kansas City Chiefs were able to escape with a 17-10 victory over the Arizona Cardinals in Week 2 of the preseason.

Joe Burrow didn't return to the field for the Cincinnati Bengals, and both groups of starters were underwhelming in the Washington Football Team's 17-13 victory.

First-round quarterback Mac Jones hasn't skipped a beat through two preseason games, and while the NFL regular season is a different beast, he looks ready to start for the New England Patriots.

While overreactions fly left and right as rookies make their NFL preseason debuts, their performance is usually non-predictive for regular-season success.

The Bills' defense is already set, but with the additions of first-round pick Greg Rousseau and second-round Boogie Basham, Buffalo just got even better.

Examining the best futures bets to make on season-long NFL Awards, from NFL MVP to comeback player of the year, ahead of the 2021 NFL season.

Cam Newton and Mac Jones led a New England offense that moved the ball at will in a 35-0 victory over the Philadelphia Eagles, who will likely be in trouble if Jalen Hurts misses any time during the regular season.

San Francisco 49ers rookie quarterback Trey Lance could see first-team reps against the Los Angeles Chargers on Friday. If and when Lance earns the starting QB job, a potential Jimmy Garoppolo trade could have ripple effects throughout the NFL.

Philadelphia Eagles offensive tackle Andre Dillard is generating interest on the trade market after all but losing the starting left tackle competition to Jordan Mailata.

New York Jets prized free agent Carl Lawson was carted off the field with a left leg injury during Thursday’s practice, per The Athletic’s Connor Hughes.

The Cincinnati Bengals are running out of time to sign star safety Jessie Bates III to a long-term contract, and it's a gamble that could backfire in a big way.

The second week of the 2021 NFL preseason has arrived. And between the 2021 rookie class, the many quarterback battles and the rosters that still need to be finalized, there is plenty to look out for in Week 2.

Odell Beckham Jr., Carson Wentz and Jamal Adams are looking to rebound from injuries, and these 29 other players need to up their game in 2021.