The Tampa Bay Buccaneers and Dallas Cowboys open up the 2021 NFL season on Thursday Night Football, with numerous betting opportunities accompanying the matchup.

Week 2 of the 2021 college football season is underway, and there are several opportunities for some valuable bets around the country. Here are some lines to keep your eyes on.

Los Angeles Chargers running back Austin Ekeler sat out of practice Wednesday, raising concerns about his status for the team's Week 1 contest against the Washington Football Team.

The Minnesota Vikings signed Brian O'Neill to a multiyear extension that will make him the NFL's second-highest-paid right tackle, the team announced Wednesday.

Indianapolis Colts head coach Frank Reich announced quarterback Carson Wentz will be a full participant in practice Wednesday. Assuming all goes well in practice this week, Wentz will play Week 1 when the Colts take on the Seattle Seahawks.

The Houston Texans have traded veteran cornerback Bradley Roby to the New Orleans Saints.

Washington Football Team tight end Sammis Reyes opens up about his unlikely journey to the NFL.

PFF's Week 2 weekday betting picks feature two Friday night matchups, including a Coastal Carolina versus Kansas bout.

Breaking down the top candidates to trade for in fantasy football before Week 1 of the 2021 NFL season, including New York Jets wide receiver Corey Davis.

Joe Thuney headlines a remade Kansas City Chiefs offensive line after the unit was the team's Achilles heel in a 2020 Super Bowl loss.

Breaking down the DFS strategies and approaches to playing the DraftKings Showdown single-game DFS contests during the 2021 NFL season.

Clemson's rudimentary rushing attack finally met its maker against a fundamentally sound Georgia run defense in Week 1 of the 2021 college football season.

The NFL preseason doesn't count toward the regular season, but it can still start put storylines into motion. Here are the players who look poised for a breakout campaign in 2021, including Miami's Tua Tagovailoa and Arizona's Byron Murphy.

Trading players is one of the best ways to improve your fantasy football team, but it can often be tough to value trade pieces. Use these charts to draft up the perfect fantasy trade.

Tampa Bay Buccaneers linebacker Lavonte David and New York Jets defensive lineman Quinnen Williams provide immense upside for the 2021 fantasy football season.

Breaking down every backfield situation heading into Week 1 for fantasy football, including Alvin Kamara and the New Orleans Saints.

PFF's Nathan Jahnke breaks down the five NFL players he's consistently drafting ahead of consensus heading into 2021 fantasy football.

Even though rosters are set, Week 1 lineups aren't, so dive into this week's fantasy football rankings to aid your efforts.