The New York Jets’ 24-20 victory over the Pittsburgh Steelers featured the 2022 debut for both Zach Wilson and rookie Kenny Pickett.

The Philadelphia Eagles looked in trouble early but bounced back to keep their unbeaten record intact, ending Week 4 with a 29-21 win over the Jacksonville Jaguars.

The Los Angeles Chargers got out to a 27-7 first-half lead and held on through the second half to beat the rallying Houston Texans 23-24 in Week 4. 

A turnover on downs, fumble and interception from the Cleveland Browns was too many mishaps to overcome as the Atlanta Falcons won, 23-20, in Week 4.

In a Week 4 divisional battle between AFC South foes, the Tennessee Titans re-established their prowess with a wire-to-wire 24-17 victory over the Indianapolis Colts.

In a game that featured two teams that will likely be in the hunt for the AFC’s top playoff seed, the Buffalo Bills claimed a hard-fought 23-20 win over the Baltimore Ravens in Week 4.

PFF staff bets in the late-Sunday window in Week 4 include the Broncos +2.5 at the Las Vegas Raiders.

The first international game of the 2022 NFL season went right down to the wire, but in the end, the Minnesota Vikings just did enough to hold on to a 28-25 victory over the New Orleans Saints.

PFF staff best bets in the early-Sunday window in Week 4 include Dallas Cowboys QB Cooper Rush u1.5 pass TDs (-160).

The live-betting opportunities in Week 4 include a Jaguars offense that tends to start slow potentially clawing its way back and keeping pace with the high-flying Eagles, writes Judah Fortgang.

Among his favorite Week 4 single game parlays, Judah Fortgang is eyeing a FanDuel SGP built around Carolina Panthers WR D.J. Moore's potential 2022 breakout game vs. the Arizona Cardinals.

Kurt Blakeway shares four potential teaser legs in Week 4, plus his favorite two-team, six-point teaser: Philadelphia Eagles -.5 / Arizona Cardinals +7.5.

The top data-driven player prop bets from Arjun Menon in Week 4 include Steelers RB Najee Harris u69.5 rush yards.

Ian Hartitz and Mario Pilato dive into injury reports around the league to bring readers the most fantasy-relevant information and analysis.

Breaking down storylines from around NFL, including New England Patriots QB Mac Jones officially being out for Sunday.

In the latest man, zone coverage analysis, an update on how often every team is playing man compared to zone, which offenses see which coverage the most, the top 10 CB trios in Perfectly Covered Plays and pressing questions in Week 4.

Five mispriced player props in Week 4, including Aaron Rodgers to go over his 0.5 interceptions prop.

The best anytime TD bets in Week 4 include Bills WR Stefon Diggs (+105) and Browns RB Kareem Hunt (+150).