PFF's Doug Kyed drops his weekly mailbag, answering questions about Mac Jones' injury status, Matthew Stafford's poor play, Trevor Lawrence's outlook this season and more.

San Francisco 49ers RB Jeff Wilson leads the charge of Nathan Jahnke's best Week 5 player prop bets.

The Indianapolis Colts kicked off Week 5 with an overtime 12-9 win over the Denver Broncos.

Breaking down storylines from around NFL, including the New England Patriots placing QB Brian Hoyer on injured reserve.

Previewing quarterback matchups, metrics and more for all 16 games on the Week 5 slate of the 2022 NFL season, including a Sunday night game between the Cincinnati Bengals and Baltimore Ravens and a Monday night showdown between the Kansas City Chiefs and the Las Vegas Raiders.

With several games completed in the 2022 NFL season already, Sam Monson reveals his early All-Pro team, which is led by Philadelphia Eagles Jalen Hurts and A.J. Brown.

Tommy Jurgens writes in his Week 5 Top spread picks not to discount the Miami Dolphins -3 at the Jets because of backup QB Teddy Bridgewater, who's an amazing 24-6 ATS on the road in his NFL Career.

With the 12th bet in our turn-$10-into-$1,000-on-BetMGM campaign, Ben Brown likes Indianapolis Colts WR Michael Pittman o5.5 receptions at plus money.

Breaking down storylines from around NFL, including Indianapolis Colts RB Jonathan Taylor being ruled out for Thursday Night Football.

Indianapolis Colts WR Michael Pittman is one of Richard Janvrin's favorite anytime TD Bets Thursday night vs. the Denver Broncos.

The Dallas Cowboys cornerbacks are performing exceptionally well — especially Trevon Diggs, who’s been one of the best in the league so far this season.

Among Kurt Blakeway's favorite two-team, six-point teasers in Week 5 is the San Francisco 49ers and their dominant defense led by Nick Bosa (from -6.5 to -.5) visiting Carolina, plus Minnesota (from -7 to -1) returning home after a narrow win in London to host the Chicago Bears.

In his first weekly column highlighting 5 live underdogs, Timo Riske writes that it makes sense to ride with the Bengals +3 at Baltimore in a high-variance spot between two inconsistent offenses in Week 5.

Dallas Cowboys left tackle Tyler Smith and Houston Texans running back Dameon Pierce are among the NFL rookies who have flashed more than their PFF grade suggests.

Kansas City QB Patrick Mahomes has overtaken Buffalo Bills QB Josh Allen as the MVP favorite after Week 4 of the 2022 NFL season, while Los Angeles Chargers QB Justin Herbert leaps to No. 5.

Breaking down the latest news and rumors after Week 4 of the 2022 NFL season, including Cooper Rush's future as an NFL quarterback, Jonathan Taylor's leg injury and 2023 NFL Draft quarterback prospects.