Matthew Stafford draws a vulnerable 49ers defense decimated by injuries and trending near the bottom of the league in disruption rate, while Justin Herbert’s increased scrambling and rushing efficiency give him a path to production even against Pittsburgh’s elite pass rush. Both quarterbacks enter Week 10 with matchups that set up favorably for efficiency-based betting angles and same-game parlay builds.

The Texans’ defense is built to disrupt Trevor Lawrence, forcing perfect coverage and quick pressure at rates among the NFL’s best — a troubling combination for a quarterback holding the ball longer and taking sacks at a high clip. With C.J. Stroud out, Davis Mills’ quick-release tendencies and a healthier receiving corps give Houston a realistic path to move the ball against a depleted Jaguars secondary.

Chris Olave, D.K. Metcalf and tight end Tyler Warren all profile as players whose target volume should rebound in Week 10 based on their route usage, quarterback tendencies and predicted target share.

Using route-level PFF data and the Predicted Targets Model, these players could be in line for large fantasy performances in Week 10.

Michelle Magdziuk breaks down five players who stand out as top last-minute waiver wire adds in fantasy football ahead of Week 10.

This fantasy football start-sit article aims to identify sleepers and the best and worst performers of the week.

Quarterbacks picked first overall enter the NFL with significant expectations. But it's best to pump the brakes and wait for their sophomore campaigns to truly assess their fantasy potential.

We dive into how trade deadline deals impact players' production with their new teams.

Week 10 is here, and PFF’s analysts have locked in their favorite bets of the week, powered by the PFF Player Prop Tool.

Utilizing the new PFF Player Prop Tool, here are two projections to target ahead of NFL Week 10 action.

Little went right on offense for the Broncos and Raiders, who battled to an ugly 10-7 result in Week 10.

Below are 10 head-to-head collisions to circle as you determine which games to prioritize watching and/or following this weekend, including Micah Parsons vs. Jordan Mailata.

Smith-Njigba's transition outside has perfectly dovetailed with Sam Darnold's arrival in Seattle, allowing the third-year receiver to explode.

A new wave of stars arrive every NFL season, some of whom assert themselves near the top of their positional rankings. As we have passed by the midway point of the 2025 NFL regular season, we can begin to identify who some of those players are.

We’re now past the midway point of the 2025 college football season, and the Heisman Trophy race is heating up.

Jon Macri provides all the red zone information fantasy football managers need to make informed decisions ahead of Week 10.