This fantasy football start-sit article aims to identify sleepers and the best and worst performers of the week.

Week 5 is here, and PFF’s analysts have locked in their favorite bets of the week, powered by the PFF Player Prop Tool.

Dealing with a bevy of injuries to key players, the 49ers rode Mac Jones and company to a hard-fought Week 5 win over the Rams.

Below are 10 wars to circle as you follow all the NFL Week 4 action, including A.J. Brown vs. Pat Surtain II.

Joseph Bryan's "Coach, I Was Open" model deducts which players could receive more targets in Week 5, including DeVonta Smith.

Using route-level PFF data and the Predicted Targets Model, these players could be in line for large fantasy performances in Week 5.

Utilizing the new PFF Player Prop Tool, here are two projections to target ahead of NFL Week 5 action.

It's still early, but we're taking stock of the Heisman Trophy race ahead of Week 6 of the 2025 college football season.

Jon Macri provides all the red zone information fantasy football managers need to make informed decisions ahead of Week 5.

Despite missing their starting quarterback, star tight end and top wide receivers, the San Francisco 49ers gutted out a hard-fought 26-23 win over the Los Angeles Rams to kick off Week 5.

PFF's fantasy football recap focuses on player usage and stats, breaking down all the vital information you need to achieve fantasy success in 2025.

We're diving into all 14 matchups in Week 5 of the 2025 NFL season — including key storylines, matchups to watch and injury news, starting with 49ers-Rams.

Michelle Magdziuk provides the top running back takeaways from Week 4 that could have a significant impact on fantasy football points in Week 5 and beyond.

Injuries, weather, and public pick releases are just a few factors that can swing numbers. But spotting early signals—before prices settle into full efficiency—is where betting edges are made. Below, we’ll walk through how notable market-maker openers have shifted since Sunday and what those moves might be telling us.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 5 contest.

At PFF, the run game matters just as much as the pass game, and every play is meticulously graded. Each week, we’ll be looking at the highest-graded run blockers and run defenders from each position.