New York Jets quarterback Zach Wilson threw four interceptions in an ugly battle between rookie signal-callers, with Mac Jones and the New England Patriots coming out on top.

The Jacksonville Jaguars needed a late kick return score to make it look respectable, but this one wasn’t close. The Denver Broncos defense was once again suffocating, and the secondary allowed nothing consistent through the air en route to a 23-13 win in Week 2 of the 2021 NFL season. 

Wide receiver Cooper Kupp and defensive lineman Aaron Donald impressed in the Los Angeles Rams' 27-24 victory over the Indianapolis Colts.

The San Francisco 49ers did just enough to squeeze by the Philadelphia Eagles in a low-scoring Week 2 affair, pushing them to 2-0 to open the 2021 NFL season.

Derek Carr led the Las Vegas Raiders to a 26-17 road win over the Pittsburgh Steelers at Heinz Field in Week 2. Carr threw for more than 350 yards for the second week in a row and added two more passing touchdowns to his season total, giving the Raiders a 2-0 start to the season. 

Quarterback Baker Mayfield and running back Nick Chubb impressed in the Cleveland Browns' 31-21 victory over the Houston Texans.

The Buffalo Bills' running backs and defensive line, including AJ Epenesa, impressed in their 35-0 victory over the Miami Dolphins.

Quarterback Sam Darnold continued his strong start to the 2021 season, leading the Carolina Panthers to a 2-0 record after taking down Jameis Winston and the New Orleans Saints.

Miami Dolphins quarterback Tua Tagovailoa appeared to be in serious pain as he limped off the field in the first quarter of Miami’s Week 2 matchup with the Buffalo Bills.

Breaking down the Week 2 fantasy football rankings and tiers for every position, including analysis, implied point totals, betting spreads and more.

PFF fantasy analyst Nathan Jahnke unveils his positional fantasy football rankings ahead of Week 2 of the 2021 NFL season.

From Spencer Rattler's disappointing day against Nebraska to Alabama's surprising two-point win over Florida, PFF sifts through some of the biggest storylines from Week 3 of the 2021 college football season.

PFF’s college football Team of the Week and player awards from Week 3 of the 2021 college football season.

Former NFL free safety Darius Butler offers his insight into the Week 2 slate and gives his favorite betting picks of the week.

Breaking down the best single-game bets and player prop bets for the Kansas City Chiefs-Baltimore Ravens Sunday night football matchup during Week 2 of the 2021 NFL season.

Your home for all of PFF's betting content ahead of Week 2 of the NFL season and Week 3 of the college football season.

Breaking down four player prop bets for the Week 2 Sunday NFL slate, including which direction to bet New York Jets quarterback Zach Wilson's 1.5 passing touchdown player prop.

Breaking down the DFS strategies and approaches to playing the DraftKings Showdown slate for the Kansas City Chiefs vs. Baltimore Ravens NFL Week 2 Sunday Night Football matchup.