NFL Week 4: Odds, lines, spreads and best bets

· Bet Cowboys QB Cooper Rush u31.5 pass attempts (-104): PFF Greenline shows 43.1% edge.

· Bet Lions WR DJ Chark u3.5 receptions vs. Seahawks (+124): 38.8% edge is the highest in Seattle-Detroit.

· Bet Browns -1.5 at Falcons: PFF Greenline shows 4.3% edge on Cleveland.

• New users who bet $10 or more at BetMGM will receive a free year’s subscription to PFF+ — a $79.99 value.

Estimated reading time: 4 mins

Take a look at the odds for every Week 4 game, courtesy of BetMGM, followed by PFF Greenline and PFF staff best bets.

Sunday, Oct. 2

Tennessee Titans @ Indianapolis Colts

· Bet: Colts RB Nyheim Hines u2.5 receptions (+131): Greenline edge of 21.7% is highest in Titans-Colts.

Chicago Bears @ New York Giants

· Bet: Bears-Giants O 38.5: PFF Greenline edge over 3%.

Buffalo Bills @ Baltimore Ravens

· Bet: Bills WR Isaiah McKenzie u2.5 receptions (+110): 13.6% edge is Greenline's largest in Bills-Ravens.

· Bet: Ravens QB Lamar Jackson o54.5 rush yards (-114): Jackson has at least 55 rushing yards in over 60% of career starts.

Los Angeles Chargers @ Houston Texans

· Bet: Texans QB Davis Mills o2.5 rush yards (-111): Nearly 10% Greenline edge.

Seattle Seahawks @ Detroit Lions

· Bet Lions WR DJ Chark u3.5 receptions vs. Seahawks (+124): 38.8% edge is the highest in Seattle-Detroit.

· Bet Seahawks WR D.K. Metcalf o5.5 receptions: He has a 91.7 PFF grade against man coverage, and his 40.9% threat rate vs. man — which Detroit plays more than any team in the league — easily the best in football.

New York Jets @ Pittsburgh Steelers

· Bet Jets RB Breece Hall u8.5 carries (-105): Greenline edge of 14.1 percent; Jets should be in comeback mode.

· Live-betting strategy: Should Steelers jump out to an opening lead of touchdown or greater, consider Zach Wilson's Jets on the back-door cover or win.

Jacksonville Jaguars @ Philadelphia Eagles

· Bet Jaguars RB Travis Ettiene u6.5 carries (-132): 15.9% Greenline edge among greatest in Jags-Eagles.

· Bet Jaguars QB Trevor Lawrence o22.5 completions (-114): Teams have passed the ball 4% more than expected on the Eagles defense (8th in NFL); likely favorable game script.

Washington Commanders @ Dallas Cowboys

· Bet Cowboys QB Cooper Rush u226.5 pass yards (-115 DK): 24.8% edge via Greenline; Washington run ‘D' 52.3 grade (26th).

· Bet Cowboys QB Cooper Rush u31.5 pass attempts (-104): PFF Greenline shows 43.1% edge.

Cleveland Browns @ Atlanta Falcons

· Bet Browns -1.5: Greenline shows 4.3% edge.

Arizona Cardinals @ Carolina Panthers

· Bet: Panthers TE Tommy Tremble o3.5 receiving yards (-120): 12.3% Greenline Edge.

· Bet: Cardinals +1:  Kliff Kingsbury has an 18-6-2 ATS record on the road; Matt Rhule has a 1-6 ATS record as a home favorite.

Denver Broncos @ Las Vegas Raiders

· Bet Davante Adams o7.5 receptions (-112): PFF Greenline edge of 12.7%..

· Bet Broncos +2.5: Take the better team and take the points.

New England Patriots @ Green Bay Packers

· Bet: Pats-Pack O 40: PFF Greenline edge of 2.7%.

Kansas City Chiefs @ Tampa Bay Buccaneers

· Bet Bucs WR Russell Gage u3.5 receptions (+110): WRs healthier, limiting target share; game-high 16.1 PFF Greenline edge.

· Bet Chiefs alt line-7.5: With big disparity between offensive capabilities, attractive spot to grab alt line before market adjustment.

Monday, Oct. 3

Los Angeles Rams @ San Francisco 49ers

· Bet 49ers RB Jeff Wilson Jr. u1.5 receptions vs. Rams (+119): 22.6% edge is Greenline's highest in Rams-Niners.