Jonathan Taylor's three touchdowns powered the Colts to a blowout win over the Raiders in Week 5.

The Vikings edged the Browns 21–17 at Tottenham Hotspur Stadium in London. Despite falling behind late, quarterback Carson Wentz led a fourth-quarter comeback, marching Minnesota down the field with key completions to wide receivers Justin Jefferson and Jordan Addison.

Dealing with a bevy of injuries to key players, the 49ers rode Mac Jones and company to a hard-fought Week 5 win over the Rams.

Below are 10 wars to circle as you follow all the NFL Week 4 action, including A.J. Brown vs. Pat Surtain II.

Despite missing their starting quarterback, star tight end and top wide receivers, the San Francisco 49ers gutted out a hard-fought 26-23 win over the Los Angeles Rams to kick off Week 5.

We're diving into all 14 matchups in Week 5 of the 2025 NFL season — including key storylines, matchups to watch and injury news, starting with 49ers-Rams.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 5 contest.

At PFF, the run game matters just as much as the pass game, and every play is meticulously graded. Each week, we’ll be looking at the highest-graded run blockers and run defenders from each position.

The Browns' unit has earned a 90.5 overall grade, led by Myles Garrett at 92.9. Maliek Collins has been dominant on the interior with a 90.2 grade — seventh-best among interior defenders — while seven Browns defenders have overall grades of 71.5 or better.

Advanced coverage grade uses machine learning to map the separation allowed on a play to the expected PFF coverage grade the player would have earned had they been targeted. This system also takes into account the difficulty of the assignment and the situation when making that assessment.

Jacksonville Jaguars cornerback Jourdan Lewis remains atop the 2025 NFL cornerback rankings through Week 4.

Nacua is picking up right where he left off last season, producing at a historic pace so far in 2025.

PFF is grading every player on every play during the 2025 NFL season, and these are the top wide receivers by PFF receiving grade through four weeks.

Line moves tell a story — the edge comes from knowing whether it’s a true signal or just an overreaction. Injuries, weather and public pick releases are just a few of the forces that can push numbers around, but the real value comes from understanding which shifts actually matter.

Drake Maye is playing with impressive efficiency — avoiding negative plays, consistently delivering the ball on time, and making smart decisions. He has cut down on the erratic misses that showed up in college and early in his rookie season and is now leading New England to dominant wins.

In this quarterback rankings breakdown, we've evaluated the top performers based on PFF passing grades. Using insights from Premium Stats, we’ll also present a variety of key grades beyond passing grade, including grades under pressure, from a clean pocket, against the blitz and more.

The Green Bay Packers' Micah Parsons ranks first in PFF pass-rush grade ahead of Week 5 of the 2025 NFL season.