The Broncos stormed back from a quiet three quarters to outscore the Eagles 18-0 in the fourth, outgaining them 156-15 in a dominant final frame. Philadelphia had one last chance, but Jalen Hurts’ Hail Mary fell incomplete in a crowded end zone, sealing Denver’s comeback win.

The Saints snapped a four-game losing streak with a 26-14 win over the Giants, earning Kellen Moore his first victory as head coach and Spencer Rattler his first as a starting quarterback. Rattler connected with Rashid Shaheed for an 87-yard touchdown — the longest Saints play since 2016 — to spark the offense. The defense also came up big, helping New Orleans move to 1-4 on the season.

The Dolphins blew a 17-point first-quarter lead in a 27-24 loss to the Panthers, falling to 1-4 on the season. Despite early success from Tua Tagovailoa and a pair of forced turnovers, Miami’s offense stalled after halftime while the defense gave up explosive plays to Carolina’s Rico Dowdle and Bryce Young. A late Panthers touchdown and Miami’s failed final possession sealed an embarrassing collapse for a team still searching for consistency.

Ryan Flournoy and Javonte Williams led the charge for the Cowboys' offense, while the team's defense limited the Jets to just three first-half points.

The injury-riddled Ravens were no match for the Texans, who have turned things around after an 0-3 start to the campaign.

Jonathan Taylor's three touchdowns powered the Colts to a blowout win over the Raiders in Week 5.

The Vikings edged the Browns 21–17 at Tottenham Hotspur Stadium in London. Despite falling behind late, quarterback Carson Wentz led a fourth-quarter comeback, marching Minnesota down the field with key completions to wide receivers Justin Jefferson and Jordan Addison.

Dealing with a bevy of injuries to key players, the 49ers rode Mac Jones and company to a hard-fought Week 5 win over the Rams.

Below are 10 wars to circle as you follow all the NFL Week 4 action, including A.J. Brown vs. Pat Surtain II.

Despite missing their starting quarterback, star tight end and top wide receivers, the San Francisco 49ers gutted out a hard-fought 26-23 win over the Los Angeles Rams to kick off Week 5.

We're diving into all 14 matchups in Week 5 of the 2025 NFL season — including key storylines, matchups to watch and injury news, starting with 49ers-Rams.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 5 contest.

At PFF, the run game matters just as much as the pass game, and every play is meticulously graded. Each week, we’ll be looking at the highest-graded run blockers and run defenders from each position.

The Browns' unit has earned a 90.5 overall grade, led by Myles Garrett at 92.9. Maliek Collins has been dominant on the interior with a 90.2 grade — seventh-best among interior defenders — while seven Browns defenders have overall grades of 71.5 or better.

Advanced coverage grade uses machine learning to map the separation allowed on a play to the expected PFF coverage grade the player would have earned had they been targeted. This system also takes into account the difficulty of the assignment and the situation when making that assessment.

Jacksonville Jaguars cornerback Jourdan Lewis remains atop the 2025 NFL cornerback rankings through Week 4.

Nacua is picking up right where he left off last season, producing at a historic pace so far in 2025.