Baker Mayfield delivered early fourth-quarter heroics to lead the Buccaneers past the 49ers, 30-19, improving Tampa Bay to 5-1. Mayfield threw two touchdown passes and extended a key drive with a spectacular third-and-14 scramble, setting up a 45-yard strike to rookie Tez Johnson for the clinching score. San Francisco, already banged up, lost star linebacker Fred Warner to a season-ending ankle injury, while Mac Jones threw for 347 yards but was picked off twice in the loss.

The high-powered Packers got back on track after their bye week, downing the languishing Bengals 27-18. Rookie Matthew Golden enjoyed a career-best day with 102 scrimmage yards, and Josh Jacobs added two more scores on the ground.

The Las Vegas Raiders picked up a much-needed victory, beating the Titans 20-12. Las Vegas' defense played arguably its best game all season, allowing only 225 total yards while forcing three turnovers. Michael Mayer also stepped up in Brock Bowers' absence with five catches for 50 yards and a touchdown, lifting Geno Smith to a more efficient performance.

The Carolina Panthers are officially on a win streak. While their rushing attack and young weapons deserve plenty of credit, the run defense's turnaround has been a major factor.

It’s hard not to wonder whether the Cowboys are second-guessing their decision to let Dowdle walk in free agency. While Carolina leaned on him as the centerpiece of a dominant rushing effort, Dallas looked lost on the ground, unable to generate push or create space for its backs.

Aaron Rodgers threw for 235 yards and two touchdowns as the Steelers cruised past the Browns 23-9, extending Cleveland’s regular-season losing streak in Pittsburgh to 22 games. Rodgers spread the ball to eight different receivers and avoided pressure all afternoon behind a solid offensive line, while rookie Dillon Gabriel was sacked six times and couldn’t find the end zone.

Drake Maye's hot run continues. The Patriots are winners of three straight after taking down the Saints in Week 6.

Sam Darnold threw two touchdown passes and Jaxon Smith-Njigba exploded for 162 receiving yards as the Seahawks beat the Jaguars 20-12 on Sunday. Seattle dominated in the trenches, sacking Trevor Lawrence seven times and holding Travis Etienne to just 27 rushing yards, while Smith-Njigba’s 61-yard score — burning new corner Greg Newsome — highlighted the day.

The upstart Colts remain the team to beat in the AFC South, taking down the Cardinals and backup quarterback Jacoby Brissett.

Bryce Young tossed three touchdowns and Rico Dowdle racked up a franchise-record 239 all-purpose yards to lift the Panthers past the Cowboys, 30-27, on a last-second field goal.

The Chargers foiled the Dolphins' late comeback attempt with some Justin Herbert-Ladd McConkey magic.

The Rams came out hot in the second half to take a two-score lead, and they didn't look back en route to a Week 6 victory.

The Broncos edged out the Jets 13-11 in a scrappy Week 6 win in London, relying on strong defense and timely field goals to improve to 4-2. Bo Nix threw a touchdown to Nate Adkins, and Wil Lutz nailed two field goals, including the go-ahead score with just over five minutes left. Denver's defense racked up nine sacks, including a game-sealer on the Jets' final drive, keeping New York winless at 0-6.

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Top SGP picks for Week 6, each tied to a clear story the data suggests could play out.

Josh Jacobs also draws a favorable matchup against a Bengals defense that ranks in the bottom 10 across nearly every major category. With one of the safest roles in football, a soft matchup and a perfect game script, there’s no need to overthink it—back Josh Jacobs to find the end zone.

Matthew Stafford has excelled against man coverage this season, averaging a dominant 0.50 EPA per play versus man coverage. He now faces a Ravens defense that plays man at one of the league’s highest rates and is arguably at its weakest point all season.

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