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The likes of Clyde Edwards-Helaire, Darrell Henderson Jr., Lamar Jackson, Mike Evans, James Robinson, Miles Sanders, Austin Ekeler, Dalvin Cook, Elijah Mitchell, D’Andre Swift, Darren Waller and Nelson Agholor are dealing with injuries/COVID situations that could cost significant time in some cases.
Darrel Williams is the must-add of the week with CEH likely out with a collarbone injury.
With James Robinson out for the remainder of the season, Dare Ogunbowale will be inserted into the Jags starting lineup as the lead running back. Ogunbowale played 83% of the snaps in Week 16, tallying 19 touches for 72 offensive yards and one touchdown.
He gets a decent matchup in Week 17 against a Patriots defense that is much weaker against running backs than opposing passing games. Entering Week 16, New England ranked fourth-worst in rushing yards allowed to running backs over the past four weeks and fourth-worst in receiving yards allowed to backs on the season.
Bills running back Devin Singletary scored 18.8 fantasy points against the Pats in Week 16.