Injuries, weather, and public pick releases are just a few factors that can swing numbers. But spotting early signals—before prices settle into full efficiency—is where betting edges are made. Below, we’ll walk through how notable market-maker openers have shifted since Sunday and what those moves might be telling us.

PFF’s media research team has been hard at work this week, preparing for kickoff — pulling data-driven insights and talking points for our broadcast partners around the league. Now, we’re sharing those same nuggets with you. So, whether you’re looking to win your fantasy matchup, hit on your bets or just get smarter about the game, these are the key storylines to know for every Week 5 contest.

At PFF, the run game matters just as much as the pass game, and every play is meticulously graded. Each week, we’ll be looking at the highest-graded run blockers and run defenders from each position.

The Browns' unit has earned a 90.5 overall grade, led by Myles Garrett at 92.9. Maliek Collins has been dominant on the interior with a 90.2 grade — seventh-best among interior defenders — while seven Browns defenders have overall grades of 71.5 or better.

Advanced coverage grade uses machine learning to map the separation allowed on a play to the expected PFF coverage grade the player would have earned had they been targeted. This system also takes into account the difficulty of the assignment and the situation when making that assessment.

Jacksonville Jaguars cornerback Jourdan Lewis remains atop the 2025 NFL cornerback rankings through Week 4.

Wondering how to handle Kenneth Walker III or Darren Waller in Week 5 fantasy football lineups? Nathan Jahnke's start-sit column has you covered.

Nacua is picking up right where he left off last season, producing at a historic pace so far in 2025.

PFF is grading every player on every play during the 2025 NFL season, and these are the top wide receivers by PFF receiving grade through four weeks.

Gain a fantasy football edge in Week 5 by targeting or avoiding these wide receivers based on their cornerback matchups.

In a battle between division rivals, Los Angeles Rams RB Kyren Williams may gain an upper hand.

Max Chadwick and Dalton Wasserman break down the biggest games of the Week 6 college football slate.

Week 5 of the 2025 NFL season is here, and so are Jon Macri's IDP fantasy football rankings.

Line moves tell a story — the edge comes from knowing whether it’s a true signal or just an overreaction. Injuries, weather and public pick releases are just a few of the forces that can push numbers around, but the real value comes from understanding which shifts actually matter.

Drake Maye is playing with impressive efficiency — avoiding negative plays, consistently delivering the ball on time, and making smart decisions. He has cut down on the erratic misses that showed up in college and early in his rookie season and is now leading New England to dominant wins.

In this quarterback rankings breakdown, we've evaluated the top performers based on PFF passing grades. Using insights from Premium Stats, we’ll also present a variety of key grades beyond passing grade, including grades under pressure, from a clean pocket, against the blitz and more.