Week 16 of the NFL DFS slate features a sure-fire RB1 week from Jacksonville Jaguars running back James Robinson and a developing rookie in Amon-Ra St. Brown, who has entered must-start territory.
Let’s dive into the best and worst Week 16 DFS plays at every position, based on matchup, opportunity, salary and roster projections.
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Quarterback
Best: Matthew Stafford, Los Angeles Rams
DK: $6,700 | FD: $7,900
After a tumultuous November, Stafford and the Rams have turned their fortune around, riding a three-game winning streak into Week 16. The veteran quarterback topped 22 fantasy points in three of his past four games, with his worst performance clocking in at 15.5 points this past week.
This week presents an excellent opportunity against a Minnesota Vikings defense that ranks 30th league-wide in passing yards allowed, 26th in passing touchdowns allowed and 27th in explosive pass percentage allowed.
Worst: Tom Brady, Tampa Bay Buccaneers
DK: $7,400 | FD: $8,400
Betting against the best player in NFL history seems like a mindless thing to do, and it might be. However, Brady has a tough matchup against the Carolina Panthers this weekend; he scored fewer than six fantasy points last week and now goes against one of the best-performing defenses in football without Chris Godwin and likely without Leonard Fournette and Mike Evans.
Brady has an exorbitant price tag. He is the third-most-expensive quarterback on the slate, according to FanDuel. I’d suggest paying down at the position or paying up for a different option.
Carolina Panthers defense vs. quarterbacks | 2021
| Category | Number (Rank) |
| Passing yards allowed | 2,779 (2nd) |
| Passing touchdowns allowed | 21 (15th) |
| Explosive pass percentage allowed | 13.0% (11th) |
| EPA per play against | -0.122 (4th) |
| Fantasy points per game allowed | 15.6 (5th) |
Running Back
Best: James Robinson, Jacksonville Jaguars
DK: $5,900 | FD: $8,200
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