In one of the bigger upsets of Week 1, the Minnesota Vikings toppled Aaron Rodgers and the Green Bay Packers, 23-7.
Offensive spotlight: In his quest to become the NFL's best wide receiver, Justin Jefferson put forth a monster Week 1 effort. He hauled in nine of his 10 targets for 184 yards and two scores, with five of those catches going for 15-plus yards. Eighty-one of his yards came after the catch.
Defensive spotlight: Safety Harrison Smith brought down an interception on a deep jump-ball from Aaron Rodgers, and he also allowed only 26 yards on five targets. All that equated to a game-high 90.4 coverage grade on first review.
Rookie spotlight: Quay Walker made two run stops on 14 run-defense snaps in his NFL debut. He was one of three Packers to earn a 70.0-plus initial run-defense grade for the contest.
Offensive line spotlight: Rookie guard Ed Ingram surrendered five pressures — one sack, three hits and one hurry — on 33 pass-blocking snaps to finish with the worst initial pass-blocking grade in the game.
Betting Summary
| Betting Odds | Closing | Result |
| Spread | MIN -1.5 | MIN Covers |
| O/U | 46.5 | Under |
Box Score
Passing
| Green Bay Packers | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Aaron Rodgers | 5.7 | 22 / 34 | 195 | 5.7 | 0 | 1 |
| Jordan Love | 2.6 | 4 / 5 | 65 | 13 | 0 | 0 |
| Minnesota Vikings | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Kirk Cousins | 19.08 | 23 / 32 | 277 | 8.7 | 2 | 0 |
Rushing
| Green Bay Packers | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| AJ Dillon | 20.1 | 10 | 45 | 4.5 | 1 | 14 |
| Aaron Jones | 10.6 | 5 | 49 | 9.8 | 0 | 29 |
| Romeo Doubs | 8.8 | 1 | 11 | 11 | 0 | 11 |
| Christian Watson | 6.1 | 1 | 7 | 7 | 0 | 7 |
| Aaron Rodgers | 5.7 | 1 | -1 | -1 | 0 | -1 |
| Minnesota Vikings | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Dalvin Cook | 13.8 | 20 | 90 | 4.5 | 0 | 16 |
| Alexander Mattison | 3.6 | 8 | 36 | 4.5 | 0 | 10 |
Receiving
| Green Bay Packers | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| AJ Dillon | 20.1 | 6 | 5 | 46 | 7.7 | 0 |
| Aaron Jones | 10.6 | 5 | 3 | 27 | 5.4 | 0 |
| Romeo Doubs | 8.8 | 5 | 4 | 37 | 7.4 | 0 |
| Robert Tonyan | 6.6 | 5 | 3 | 36 | 7.2 | 0 |
| Christian Watson | 6.1 | 4 | 2 | 34 | 8.5 | 0 |
| Josiah Deguara | 4.8 | 2 | 2 | 28 | 14 | 0 |
| Sammy Watkins | 4.8 | 3 | 3 | 18 | 6 | 0 |
| Randall Cobb | 3.4 | 3 | 2 | 14 | 4.7 | 0 |
| Juwann Winfree | 2.7 | 1 | 1 | 17 | 17 | 0 |
| Tyler Davis | 1.3 | 1 | 1 | 3 | 3 | 0 |
| Minnesota Vikings | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Justin Jefferson | 42.4 | 11 | 9 | 184 | 16.7 | 2 |
| Dalvin Cook | 13.8 | 5 | 3 | 18 | 3.6 | 0 |
| Adam Thielen | 6.6 | 4 | 3 | 36 | 9 | 0 |
| Johnny Mundt | 4.7 | 3 | 3 | 17 | 5.7 | 0 |
| K.J. Osborn | 4.4 | 4 | 3 | 14 | 3.5 | 0 |
| C.J. Ham | 1.6 | 1 | 1 | 6 | 6 | 0 |
| Ben Ellefson | 1.2 | 1 | 1 | 2 | 2 | 0 |
| Irv Smith Jr. | 0 | 2 | 0 | 0 | 0 | 0 |
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