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NFL Betting 2022: Week 17 spread picks to bet before lines move

Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) throws a pass during the first quarter against the Washington Commanders at Levi's Stadium. Mandatory Credit: Sergio Estrada-USA TODAY Sports

• Bet the San Francisco 49ers (-5.5) at the Las Vegas Raiders: Rookie quarterback Brock Purdy continues to excel as the 49ers' starter, and Nick Bosa has a delectable matchup as a pass rusher.

• Bet the over (47) in Minnesota Vikings at Green Bay Packers: The Vikings' and Packers' offenses can be lethal when in rhythm, and their defenses are susceptible to giving up points.

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Estimated Reading Time: 5 mins

Editor's Note: Betting lines are accurate as of post-Sunday Night Football.

San Francisco 49ers (-5.5) @ Las Vegas Raiders

Why to bet:

The great Brock Purdy has earned a better PFF grade this season (71.8) than Derek Carr. The 49ers' offense is going up against a Raiders defense that has just one player with a 75.0-plus PFF grade (that being edge rusher Maxx Crosby). The 49ers should have no problem scoring on the Raiders.

On the other side of the ball, the 49ers' defense and Nick Bosa will have key advantages that should put Carr under frequent pressure. Bosa sports the second-highest PFF grade (91.1) among edge rushers. He will face Las Vegas' Jermaine Eluemunor, who ranks 37th in PFF grade among all tackles this season. That's no match for Bosa.

Why to be wary:

Raiders wide receiver Davante Adams could come back to life and put together a signature game after being inconsequential over the past couple of weeks. Adams still boasts a top-10 PFF grade (88.9) and could take advantage of 49ers defensive backs not named Charvarius Ward.


Minnesota Vikings @ Green Bay Packers over 47.0

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