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Best last-minute NFL bets ahead of Week 2

Indianapolis, Indiana, USA; Indianapolis Colts running back Nyheim Hines (21) runs the ball in the second half against the Seattle Seahawks at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-USA TODAY Sports

Late-week betting action isn’t the best approach if long-term profitability is the goal. Game spreads and totals become increasingly sharp moving closer to kickoff, which is why betting game lines early in the week is the best approach. 

If betting early in the week isn’t an option, then targeting other markets where lines aren’t stale is key. Beating these markets takes a different approach than those focused solely on the game lines.

We can take cues from bookmakers pricing the entire portfolio of offerings on a particular matchup, as they arrive at a most likely path the game will travel and then use market dynamics to sharpen the number. In some way, game lines feed derivatives, player props and most other offerings under that matchup umbrella.


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We can start by seeing if there are any game lines we disagree with and utilize a couple of different approaches if so.

Mispriced scenarios should continue to be mispriced further downstream as errors compound. Or, if the game line is only subtly off, it's smart to find where its errors are the most drastic.

Using these approaches, let's find the best last-minute NFL bets ahead of Week 2.

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