The Jaguars put a decisive end to the Broncos' 11-game winning streak, winning 34-20 and inching closer to the top seed in the AFC. Trevor Lawrence remained on fire with 279 yards and three touchdowns, and Parker Washington enjoyed a career day with 145 yards and a score. Two Broncos turnovers also fueled a win for arguably the league's hottest team.

The Texans held off the resilient Raiders to win their seventh straight game. Derek Stingley Jr. returned a Geno Smith interception 31 yards to open the scoring, and Houston capitalized on nine Las Vegas penalties to win despite two long touchdowns from Ashton Jeanty.

The Falcons' offense continued to roll against the Cardinals in their 26-19 victory. Atlanta totaled 197 rushing yards with an average of 9.4 yards per carry, and Bijan Robinson accrued 168 yards from scrimmage.

Joe Burrow bounced back from his first career shutout by throwing for 309 yards and four touchdowns as the Bengals turned a tight first half into a 45-21 rout of the Dolphins, scoring 28 points off four straight turnovers. Chase Brown scored three touchdowns in the third quarter alone, while Miami unraveled in the second half behind rookie starter Quinn Ewers despite a strong early showing.

J.J. McCarthy ran for a touchdown but left late in the first half with a right-hand injury after a strip sack turned into a Giants defensive touchdown, before backup Max Brosmer guided the Vikings to a go-ahead fourth-quarter field goal in a 16-13 win. Minnesota won its third straight while New York lost its ninth in a row, managing only two field goals and a scoop-and-score as the offense sputtered behind rookie quarterback Jaxson Dart.

Already eliminated from playoff contention, the Cowboys competed early but couldn’t keep pace as the Chargers pulled away for a 34-17 win behind Justin Herbert’s efficient 300-yard, two-touchdown performance. Dak Prescott threw two scores and George Pickens topped 130 receiving yards, but Los Angeles controlled the game statistically and physically, outgaining Dallas, dominating time of possession, and finishing drives more effectively.

Rookie Tyler Shough continues to improve, helping the Saints win their third straight game after a 2-10 start to the season.

Bryce Young threw two touchdown passes and Lathan Ransom sealed the game with a late interception as the Panthers beat the Buccaneers 23-20 to move into first place in the NFC South. Carolina took the lead on a fourth-quarter field goal and turned away Tampa Bay’s final drive, putting itself in position to clinch the division with help next week.

The Titans earned their third win in a difficult season through a strong defensive effort and a clean showing from rookie quarterback Cam Ward.

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The Bills stayed on a roll by squeaking by the Browns. James Cook tallied 117 yards and two touchdowns against one of the league's premier run defenses, and Buffalo's defense intercepted Shedeur Sanders twice.

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Jacksonville’s ability to generate pressure with four-man rushes puts the Broncos offense in a tough spot, as Bo Nix has struggled badly when defenses don’t blitz — a direct clash with the Jaguars’ biggest defensive strength. On the other side, Trevor Lawrence’s recent shift toward aggressive downfield passing lines up perfectly against a Denver defense that allows one of the league’s highest deep-attempt rates.

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Count on the Patriots' Stefon Diggs to return to form against a Ravens defense that has been allowing significant production to wide receivers lately.

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The Bears survived a game they trailed for most of the night by capitalizing late, rallying for a 22-16 overtime win over the Packers to move to 11-4. A recovered onside kick, clutch execution from Caleb Williams and DJ Moore, and steady kicking from Cairo Santos flipped the game in the final minutes and sealed a critical division victory.