The San Francisco 49ers emerged with an expected victory over the Carolina Panthers on the road in Week 5, heading home with a 37-15 win.
Offensive spotlight: The 49ers rushing attack accounted for 154 yards in total, with Jeff Wilson Jr. notching 120 yards on 17 carries. He had four explosive runs of 10 or more yards and 75 yards before contact in the game.
Defensive spotlight: 49ers cornerback Charvarius Ward had an elite game against this struggling Panthers passing attack. Ward was thrown at six times, allowing one catch for 32 yards. He had four forced incompletions overall.
Rookie spotlight: Nick Bosa going down with a groin injury didn’t hurt Panthers first-round rookie Ikem Ekwonu, and he had an excellent game. He allowed just a couple of pressures across 35 pass-blocking snaps and graded out well in the run game, pending review.
Offensive line spotlight: San Francisco’s offensive line isn’t necessarily playing particularly well individually, but the unit does an excellent job of scheming around the problems and limiting any negative plays that would otherwise come from it. Jimmy Garoppolo was sacked just twice.
Box Score
Passing
| San Francisco 49ers | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Jimmy Garoppolo | 18.02 | 18 / 30 | 253 | 8.4 | 2 | 0 |
| Carolina Panthers | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Baker Mayfield | 7.6 | 20 / 36 | 215 | 6 | 0 | 1 |
| PJ Walker | 2.4 | 5 / 6 | 60 | 10 | 0 | 0 |
Rushing
| San Francisco 49ers | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Jeff Wilson Jr. | 23.2 | 17 | 120 | 7.1 | 1 | 41 |
| Tevin Coleman | 21.7 | 8 | 23 | 2.9 | 1 | 14 |
| Jimmy Garoppolo | 18.02 | 1 | -1 | -1 | 0 | -1 |
| Deebo Samuel | 11.2 | 2 | 12 | 6 | 0 | 9 |
| Brock Purdy | -0.1 | 1 | -1 | -1 | 0 | -1 |
| Carolina Panthers | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Christian McCaffrey | 23.4 | 14 | 54 | 3.9 | 1 | 19 |
| DJ Moore | 10.7 | 1 | 8 | 8 | 0 | 8 |
| D'Onta Foreman | 0.2 | 2 | 2 | 1 | 0 | 5 |
Receiving
| San Francisco 49ers | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Jeff Wilson Jr. | 23.2 | 2 | 1 | 12 | 6 | 0 |
| Tevin Coleman | 21.7 | 3 | 3 | 44 | 14.7 | 1 |
| Deebo Samuel | 11.2 | 9 | 2 | 20 | 2.2 | 1 |
| Brandon Aiyuk | 8.8 | 4 | 3 | 58 | 14.5 | 0 |
| George Kittle | 8.7 | 6 | 5 | 47 | 7.8 | 0 |
| Jauan Jennings | 6.5 | 2 | 2 | 45 | 22.5 | 0 |
| Kyle Juszczyk | 4.7 | 2 | 2 | 27 | 13.5 | 0 |
| Danny Gray | 0 | 2 | 0 | 0 | 0 | 0 |
| Carolina Panthers | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Christian McCaffrey | 23.4 | 12 | 7 | 50 | 4.2 | 0 |
| Shi Smith | 10.9 | 5 | 4 | 69 | 13.8 | 0 |
| DJ Moore | 10.7 | 8 | 4 | 59 | 7.4 | 0 |
| Terrace Marshall Jr. | 7 | 4 | 4 | 30 | 7.5 | 0 |
| Giovanni Ricci | 5.7 | 3 | 3 | 27 | 9 | 0 |
| Robbie Anderson | 4.2 | 5 | 1 | 32 | 6.4 | 0 |
| Ian Thomas | 2.8 | 2 | 2 | 8 | 4 | 0 |
| Tommy Tremble | 0 | 1 | 0 | 0 | 0 | 0 |
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