In a rain-soaked season opener at Soldier Field, the Chicago Bears reeled off 19 straight points to upset the San Francisco 49ers, 19-10, to get their 2022 season started on the right foot.
Offensive spotlight: While Justin Fields didn’t register the best initial offensive (47.0) or passing (39.8) grades on the afternoon, his rushing grade (65.8) carried the Bears’ offense during murky weather conditions. The Ohio State product scrambled for three first downs and forced two missed tackles alongside his two big-time throws that resulted in passing scores.
Defensive spotlight: On 50 total snaps, Talanoa Hufanga served as the Niners' best defensive player. The second-year safety registered six defensive stops, a tackle for loss and an interception en route to a pending 90.9 defensive grade.
Rookie spotlight: Edge defender Dominique Robinson played only 20 defensive snaps, but he was a constant disruptive factor along the Bears’ frontline. The fifth-round selection from Miami (OH) had three total pressures, including two sacks, during his NFL debut to earn a pending 77.2 pass-rushing grade.
Offensive line spotlight: Tevin Jenkins was more of a run-blocking factor than a pass-blocking one, but he still finished with an 81.7 offensive grade on 32 total snaps, pending review. His pass-protection resume consisted of just one pressure allowed on 13 pass-blocking plays, and he registered a 78.7 run-blocking grade on 18 run-blocking snaps.
Betting Summary
| Betting Odds | Closing | Result |
| Spread | SF -6.5 | CHI Covers |
| O/U | 37.5 | Under |
Box Score
Passing
| San Francisco 49ers | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Trey Lance | 10.96 | 13 / 28 | 164 | 5.9 | 0 | 1 |
| Chicago Bears | ||||||
| Player | Fantasy | Comp/Att | Yds | YPA | TD | Int |
| Justin Fields | 14.64 | 8 / 17 | 121 | 7.1 | 2 | 1 |
Rushing
| San Francisco 49ers | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Deebo Samuel | 13.6 | 8 | 52 | 6.5 | 1 | 27 |
| Trey Lance | 10.96 | 13 | 54 | 4.2 | 0 | 13 |
| Brandon Aiyuk | 6.7 | 1 | 7 | 7 | 0 | 7 |
| Jeff Wilson Jr. | 5 | 9 | 22 | 2.4 | 0 | 5 |
| Elijah Mitchell | 4.1 | 6 | 41 | 6.8 | 0 | 16 |
| Chicago Bears | ||||||
| Player | Fantasy | Car | Yds | YPC | TD | Long |
| Justin Fields | 14.64 | 11 | 28 | 2.5 | 0 | 12 |
| Khalil Herbert | 11.3 | 9 | 45 | 5 | 1 | 12 |
| David Montgomery | 8 | 17 | 26 | 1.5 | 0 | 6 |
Receiving
| San Francisco 49ers | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Deebo Samuel | 13.6 | 8 | 2 | 14 | 1.8 | 0 |
| Jauan Jennings | 10.2 | 6 | 4 | 62 | 10.3 | 0 |
| Brandon Aiyuk | 6.7 | 2 | 2 | 40 | 20 | 0 |
| Jeff Wilson Jr. | 5 | 2 | 2 | 8 | 4 | 0 |
| Ray-Ray McCloud III | 3 | 2 | 1 | 20 | 10 | 0 |
| Ross Dwelley | 2.1 | 2 | 1 | 11 | 5.5 | 0 |
| Tyler Kroft | 1.9 | 2 | 1 | 9 | 4.5 | 0 |
| Kyle Juszczyk | 0 | 2 | 0 | 0 | 0 | 0 |
| Chicago Bears | ||||||
| Player | Fantasy | Tgt | Rec | Yds | YPT | TD |
| Dante Pettis | 12.1 | 1 | 1 | 51 | 51 | 1 |
| Khalil Herbert | 11.3 | 1 | 1 | -2 | -2 | 0 |
| Equanimeous St. Brown | 8.8 | 3 | 1 | 18 | 6 | 1 |
| David Montgomery | 8 | 4 | 3 | 24 | 6 | 0 |
| Byron Pringle | 3.2 | 2 | 1 | 22 | 11 | 0 |
| Darnell Mooney | 1.8 | 3 | 1 | 8 | 2.7 | 0 |
| Ryan Griffin | 0 | 2 | 0 | 0 | 0 | 0 |
| Cole Kmet | 0 | 1 | 0 | 0 | 0 | 0 |
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