NFL Betting 2022: Odds, spreads, best bet for preseason Week 3 Thursday slate

Kansas City, Missouri, USA; Kansas City Chiefs tight end Travis Kelce (87) runs the ball against Green Bay Packers inside linebacker De'Vondre Campbell (59) during the second half at GEHA Field at Arrowhead Stadium. Mandatory Credit: Jay Biggerstaff-USA TODAY Sports

By PFF.com
Posted Aug 25, 2022 11:46 am EDT

• Best Bet: 49ers vs. Texans Under 40.5

• All odds and game spreads courtesy of BetMGM

• All PFF+ subscribers now have access to our revamped Fantasy Football Draft Guide, which has all the streamlined and intuitive features you’ll need to dominate your draft this season. CLICK HERE TO SIGN UP FOR PFF+ AND TRY IT FREE TODAY

Green Bay Packers at Kansas City Chiefs

	Spread	Total	Moneyline
Green Bay Packers	-1.5 (-110)	O 37.5 (-110)	-130
Kansas City Chiefs	+1.5 (-110)	U 37.5 (-110)	+105

San Francisco 49ers at Houston Texans

	Spread	Total	Moneyline
San Francisco 49ers	-3 (-110)	O 40.5 (-110)	-165
Houston Texans	+3 (-110)	U 40.5 (-110)	+135

Bet the under 40.5: We can expect to see a bit more efficiency on the offensive side of the ball from both of these teams with the starters due extra playing time, but both offenses have struggled so far despite 2-0 starts. The total is high enough for two teams with offensive success still to prove. Defense has not been a problem so far.

Best Bets

PFF's Best Bets Tool reveals the bets PFF's data and algorithms give the biggest edge to within spread, total, player prop, and moneyline markets.

Available with
Player Props

PFF's Player Props Tool reveals betting opportunities within player prop markets.

Available with
NFL Power Rankings

Power Rankings are PFF’s NFL power ratings based on weekly player grades in each facet of play. These power rankings are adjusted based on coach, quarterback and the market each season.

Available with
NFL Greenline

PFF predictions and real time spread, moneyline and over/under lines for each NFL game.

Available with
NCAA Greenline

PFF predictions and real time spread, moneyline and over/under lines for each NCAA game.

Available with