- Jacksonville Jaguars vs. Indianapolis Colts: Jacksonville should run the ball voluminously in an expected blowout.
- Cincinnati Bengals vs. Tennessee Titans: No team has been run on more than the Titans.
- Los Angeles Chargers vs. Los Angeles Rams: Both backfields could play productively.

Games featuring two high-powered offenses and/or defensive disadvantages can create favorable fantasy football matchups that increase a given player’s potential fantasy-scoring output. Identifying these ahead of time gives fantasy managers an edge over the competition. The article below breaks down three running game matchups to target in Week 8.