- Malik Nabers appears ready to play: The New York Giants‘ release of Darius Slayton is a sign the Giants are confident in Nabers, and he starts the season with a great matchup.
- Sit Brock Purdy: The San Francisco 49ers quarterback is the first of many that you will usually start, unless they are playing the Los Angeles Rams.
- Introducing the NEW PFF Pro subscription: PFF Pro includes everything in PFF+, plus an upgraded Premium Stats Pro experience, higher base access to Guru AI, revamped player and team pages, enhanced data and visualizations, an improved interface and programmatic data access for modeling. Click here to subscribe.

Estimated Reading Time: 22 minutes
I asked fantasy managers on Bluesky and X which players they are least sure about this week, and I compiled that list and ranked them against one another. If you have multiple players mentioned, you should start with the player ranked highest. At the bottom of each position, you'll find players to start over the featured players and those to sit in favor of them.
If a player isn’t mentioned, that means they are very close to those with blurbs, and factors like injuries on the opposing defenses or weather could influence the rankings. Situations involving injuries are also generally avoided because things typically don't become clearer until closer to kickoff. As always, check the weekly PFF fantasy rankings for the most up-to-date information to help you make all start-sit decisions.