- Kansas City Chiefs at Buffalo Bills: The two teams’ corresponding offensive and defensive injuries could prove pivotal.
- Seattle Seahawks at Washington Commanders: The game features two highly efficient offenses, though their offensive strengths differ.
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Estimated Reading Time: 7 minutes

The report below identifies fantasy-friendly and unfriendly NFL offenses while breaking down possible outcomes from each week’s offensive matchups.
Highlighted statistical variables include neutral game pass play and run play rates, success rate, expected points added (EPA) per play, shifts, motion and play-action pass play usage, offensive play volume and pace.
Neutral game run play rate and neutral game pass play rate
Offensive neutral game run and pass play percentages among NFL teams:
