NFL Week 7 Betting: Five best PrizePicks plays

• Bet Patrick Mahomes OVER 295.5 passing yards: Bet on Mahomes to light up a Chargers secondary giving up nearly 300 yards a game through the air.

• Bet D.J. Moore OVER 4.5 receptions: Chicago will likely have to feed D.J. Moore to get something going through the air with Justin Fields out.

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If you have never played PrizePicks, you are in for a treat. You choose two or more players from the board and whether they go over or under their projected fantasy score or single stat. The payout increases with each leg added, similar to a parlay bet.

For each week of the 2023 NFL season, we'll be making a list of our favorite picks. You can take these picks and make a two-, three-, four- or five-leg entry. Let’s get started ahead of Week 7.

Patrick Mahomes OVER 295.5 passing yards

In the past three meetings against the Chargers, Patrick Mahomes has thrown for 974 yards, eight touchdowns and just one interception. Many are discounting the Chiefs' offense right now, but bet on Mahomes to light up a Chargers secondary giving up nearly 300 yards a game through the air.

Josh Reynolds over 2.5 receptions

Josh Reynolds has been an unsung hero for the Lions this season. He is currently the 15th-highest-graded wide receiver in the NFL and has reached over 2.5 receptions in every game this season.

Justin Tucker + Riley Patterson UNDER 3.5 Field Goals (combination)

We just need these two to make fewer than four field goals. I’m a sicko.

Lamar Jackson + Mark Andrews over 110.5 yards (combination of rushing and receiving)

The duo has hit this mark in two straight games. If the Ravens' offense is going to find some kind of rhythm, it will come through these two.

D.J. Moore over 4.5 receptions

With Justin Fields out this week, the Bears' offensive outlook is bleak. Despite this, Chicago will likely have to feed D.J. Moore to get something going through the air.