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Quenton Nelson was one of the Colts' best players in this one. He dominated as both a run-blocker and pass-blocker, opening up rushing lanes for the Colts' backs and keeping Jacoby Brissett upright in the process.
Khari Willis played well against the run and limited his mistakes in coverage on his way to an overall strong performance in Week 2.
In what has become the norm, linebacker Darius Leonard led the team in tackles and picked up a sack against Tennessee. With that said, he did not have a strong game in coverage and was responsible for the Titans' first touchdown of the game in the first half.
The Colts' defense, as a whole, did a great job of limiting big plays all afternoon. The defensive backs buckled down late in the fouth when it appeared as though the Titans were driving for a potential game-winning field goal that instead resulted in a turnover on downs.
As mentioned above, Willis had a strong game against Tennessee. He's a name to watch for Indy moving forward.
This one will be a tough pill to swallow for the Titans' defense. The unit played well for most of the game but fell victim to the big play too many times to shut out the Colts' offense.
The box score will look better than how Marcus Mariota performed in this one. On more than one occasion Mariota was holding the ball too long in the pocket and taking a sack, and he got away with a couple of dangerous throws that fell incomplete. Additionally, Mariota fumbled deep in his own end of the field, but the offense was able to recover.
Derrick Henry had an up-and-down day against the Colts, scoring a touchdown and breaking off a few nice runs. But he also fumbled and dropped a pass as well.
After a strong outing against Denzel Ward and the Cleveland Browns in Week 1, rookie Ole Miss product AJ Brown had just three receptions for 25 yards against Indy.