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NFL Week 6 Fantasy football and DFS targets and fades: Joe Burrow, A.J. Brown and more

Cincinnati Bengals quarterback Joe Burrow (9) throws in the first quarter of a Week 5 NFL football game against the Green Bay Packers, Sunday, Oct. 10, 2021, at Paul Brown Stadium in Cincinnati. Green Bay Packers At Cincinnati Bengals Oct 10

PFF’s grades and advanced research tools bring a wealth of data and information to all types of football fans. And with that data, we can identify fantasy football value plays and potential breakouts to help provide a huge edge over your competition. 

Last week, PFF ranked Lamar Jackson as the No. 2 signal-caller and advised caution with Clyde Edwards-Helaire. Byes complicate things in Week 6, but there are still some players who stand out in our Week 6 fantasy football rankings.

Note: Rankings based on PPR scoring

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Target: QB Joe Burrow, Cincinnati Bengals

PFF WK6 Consensus Rank: QB8
Opponent: @ Detroit Lions

Following Cincinnati’s Week 5 loss to the Green Bay Packers, Burrow was sent to the hospital for a throat contusion. However, that’s not expected to be a factor this week. Listed as PFF’s No. 8-graded signal-caller for the season, Burrow should be fully healthy and poised to deliver another excellent outing against a moribund Detroit defense that ranks dead last in PFF coverage grade.

In all five games played so far this season, Burrow has tossed multiple touchdowns. His 11 total touchdowns on the season rank eighth, despite the fact that he's attempted only 145 passes, which is tied for 26th. 

The Bengals are also dealing with a short-handed backfield, which will put more emphasis on Burrow and the passing attack. That should lead to a game script that features the second-year quarterback throwing the ball early and often against a vulnerable Lions secondary.

In addition to ranking 32nd in coverage, Detroit has ceded 24.3 fantasy points per game to quarterbacks at home this season. With his consistency at getting the ball into the end zone and a 57% chance at topping 300 passing yards, Burrow is poised to deliver elite fantasy numbers in Week 6.

Fade: QB Kirk Cousins, Minnesota Vikings 

PFF WK6 Consensus Rank: QB17
Opponent: @ Carolina Panthers

Cousins was a big disappointment last week, even though the Vikings pulled off a last-second win. Before he can rebound and re-enter the weekly QB1 conversation, he’s more likely to struggle again this week, traveling to Carolina to face a Panthers’ defense that has yielded the 10th-fewest fantasy points to opposing passers.

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