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Fantasy Football: 5 WR/CB matchups to target and 5 WR/CB matchups to avoid in Week 16

Arlington, Texas, USA; San Francisco 49ers wide receiver Brandon Aiyuk (11) celebrates after scoring a touchdown against the Dallas Cowboys in the second quarter at AT&T Stadium. Mandatory Credit: Tim Heitman-USA TODAY Sports

Welcome to our second-to-last week covering the wide receiver and cornerback battles to target. Good luck in your fantasy championships, and may the DFS gods bless you with some Christmas winnings.

After analyzing the NFL’s Week 16 slate of games, I’ve compiled my list of the most and least desirable wide receiver and cornerback matchups to target, with the help of PFF's WR and CB matchup chart.

5 WR/CB Matchups to Target

Tampa Bay Buccaneers WR Chris Godwin vs. Detroit Lions CB Justin Coleman

The Bucs are a hard team to decipher for fantasy purposes, specifically at the wide receiver position. From Weeks 11-12 and 14-15, Godwin ranked third among the team’s receivers with 18 targets, but he managed to remain productive by pulling in 13 receptions for 114 receiving yards and two touchdowns en route to 36.4 fantasy points.

While he appears to have taken somewhat of a backseat to his running mates, Godwin will see a favorable matchup in Week 16 against Coleman. Both players will align in the slot position, with Coleman having allowed a respectable 0.27 fantasy points per route and Godwin being handed the second-strongest advantage of the week — at 55%, per PFF’s WR and CB matchup chart.

Dallas Cowboys WR CeeDee Lamb vs. Philadelphia Eagles CB Nickell Robey-Coleman

Lamb — an explosive rookie receiver — doesn’t operate within a featured role like many other wideouts on this list and in the league. However, he still ranks second on the Cowboys’ offense in fantasy points (178.7) this season and still tops the list among the trio of No. 1 wide receivers with his 12 end-zone targets.

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