- Detroit Lions–Cincinnati Bengals: Detroit’s offense could produce two top-24 running back finishes in Week 5.
- Dallas Cowboys–New York Jets: Both teams could throw more than expected.
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Estimated Reading Time: 7 minutes

The report below identifies fantasy-friendly and unfriendly NFL defenses.
Highlighted statistical variables include success rate allowed, expected points added (EPA) allowed per play, explosive plays allowed, offensive plays allowed per game, offensive pass play rate faced, quarterback pressure rate and blitz rate.
Success rate allowed and EPA per play allowed
Success rate allowed and EPA allowed per play among NFL teams:

Among NFL defenses, the Cleveland Browns allow the league’s lowest offensive success rate and the Minnesota Vikings allow the fewest EPA per play. Cleveland ranks in the bottom-third among NFL defenses in explosive pass plays allowed and ties for the lowest explosive run plays allowed. Minnesota’s run defense keeps Cleveland’s condensed rushing attack fantasy-viable regardless of the game script. Minnesota and Cleveland’s fantasy defense/special teams (D/ST) units wield starkly contrasting pass rush tactics. Both can achieve elite results. The Vikings’ offensive line injuries are more severe than the Browns’. A fast offensive pace remains likely for Cleveland, regardless of the starting quarterback.
Cleveland’s inefficient offense lost its No. 2 target earner. Minnesota’s defense ties for the 11th most receptions allowed to opposing tight ends (20).