NFL News & Analysis

NFL Week 11 Game Recap: San Francisco 49ers 38, Arizona Cardinals 10

Mexico City, MEXICO; San Francisco 49ers tight end George Kittle (85) celebrates his touchdown reception against the Arizona Cardinals with quarterback Jimmy Garoppolo (10) during the second quarter at Estadio Azteca. Mandatory Credit: Kirby Lee-USA TODAY Sports

Unfortunately for the NFL’s Mexican audience, they didn’t get much of a game on Monday night.

The San Francisco 49ers routed the Arizona Cardinals 38-10 in Mexico City. With the win, the 49ers move to 6-4 and take over first place in the NFC West from the Seattle Seahawks. Meanwhile, the Cardinals are now 4-7.

Offensive spotlight:  George Kittle could not be stopped by the Cardinals. He scored two touchdowns on just four catches, with a game-high 149.3 passer rating when targeted. His 88.8 grade on first review is currently a season-high.

Defensive spotlight: Nick Bosa may get all the love, but his teammate Charles Omenihu was the one who dominated as a pass-rusher. The fourth-year 49ers edge defender had an 85.2 pass-rushing grade on first review, nearly 20 points higher than any other defender on Monday night. He picked up six pressures on 33 pass-rushing snaps to go along with a 30.3% pass-rush win rate.

Rookie spotlight: Among tight ends on Monday night, Trey McBride had a much quieter night than Kittle.

The Cardinals’ second-rounder was thrust into the starting lineup this week with Zach Ertz out for the season with a knee injury. McBride caught all four of his targets, but they only went for 14 yards. 

Offensive line spotlight: Trent Williams continues to look like the best offensive lineman in football.

After setting the PFF record last season for the highest-graded season by any player (96.6), Williams “regressed” to only an 89.5 grade heading into tonight, still the third-best among tackles. 

That grade will certainly move up after his game against the Cardinals. Williams currently has a 94.2 grade on first review, which would be the highest of his 12-year career. His 96.2 run-blocking grade on first review would also be a career-high. 

Highest-graded games of Trent Williams’ career
Year Week Opponent Grade
2022 11 Arizona Cardinals 94.2*
2021 10 Los Angeles Rams 94.1
2021 8 Chicago Bears 92.7

Box Score

Passing
San Francisco 49ers
Player Fantasy Comp/Att Yds YPA TD Int
Jimmy Garoppolo 25.42 20 / 29 228 7.9 4 0
Arizona Cardinals
Player Fantasy Comp/Att Yds YPA TD Int
Colt McCoy 8.32 24 / 34 218 6.4 0 1
Trace McSorley 1.96 6 / 10 59 5.9 0 1
Rushing
San Francisco 49ers
Player Fantasy Car Yds YPC TD Long
Jimmy Garoppolo 25.42 1 3 3 0 3
Deebo Samuel 22.4 3 37 12.3 1 39
Christian McCaffrey 17.6 7 39 5.6 0 20
Elijah Mitchell 5.9 9 59 6.6 0 19
Jordan Mason 1.4 4 14 3.5 0 8
Brock Purdy 0.5 1 5 5 0 5
Kyle Juszczyk 0.4 1 4 4 0 4
Arizona Cardinals
Player Fantasy Car Yds YPC TD Long
James Conner 13.4 14 42 3 1 14
Colt McCoy 8.32 3 6 2 0 4
Trace McSorley 1.96 1 6 6 0 6
Keaontay Ingram 1.9 5 19 3.8 0 13
Rondale Moore -0.6 1 -6 -6 0 -6
Receiving
San Francisco 49ers
Player Fantasy Tgt Rec Yds YPR TD
George Kittle 24.4 6 4 84 21 2
Deebo Samuel 22.4 9 7 57 8.1 0
Christian McCaffrey 17.6 7 7 67 9.6 0
Brandon Aiyuk 16 4 2 20 10 2
Ray-Ray McCloud III 0 1 0 0 0 0
Jauan Jennings 0 2 0 0 0 0
Arizona Cardinals
Player Fantasy Tgt Rec Yds YPR TD
Greg Dortch 22.3 10 9 103 11.4 0
DeAndre Hopkins P 18.1 12 9 91 10.1 0
James Conner 13.4 5 2 12 6 0
A.J. Green 10 9 5 50 10 0
Trey McBride 5.4 4 4 14 3.5 0
Maxx Williams 1.7 1 1 7 7 0
Stephen Anderson 0 1 0 0 0 0

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