NFL Week 13 Injury Report: All 14 games

A player's injury status can have a significant effect on both real life and fantasy football. So, each week, PFF injury analyst Mario Pilato will comb through the official injury reports for each NFL game and give updates and analysis for fantasy-relevant players.

Injuries are fluid, so make sure to stay up to date by following @PFF_Mario on Twitter.

KEY
DNP: Did not participate in practice
LP: Limited participation in practice
FP: Full participation
(-): Not listed
OUT: Player will not play
D: Player is unlikely to play
Q: Player is not certain to play
NIR – Rest: Not injury-related or resting veteran

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Dallas Cowboys @ New Orleans Saints (+4.5)

The Over/Under for this game is currently 47.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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New York Giants @ Miami Dolphins (-6)

Injury Analysis: Giants WRs Sterling Shepard and Karadius Toney are doubtful with quad injuries, and I do not expect them to play.  WR John Ross recorded two DNPs and then got in a limited session due to an illness. He is questionable but trending in the right direction. QB Daniel Jones has been ruled out with a neck injury.

Dolphins RB Phillip Lindsay is doubtful with an ankle injury, and I do not expect him to play in Week 13.

Fantasy Analysis:  DeVante Parker has been activated off IR and should be be active for Week 13. Parker leads Miami with a 23% target share in his five healthy game played this season ahead of Jaylen Waddle (21%).

In Parker's two games played with Tua Tagovailoa at quarterback, he has totaled 19 targets, 12 receptions and 166 receiving yards. He is way too cheap on DraftKings at $3,900.

Don’t overlook Miami Dolphins’ actual TE1 Durham Smythe with Mike Gesicki being miscategorized as a tight end.

With Adam Shaheen sidelined by an injury, Smythe played 89.5% of the snaps and caught five of five targets for 32 receiving yards. He is the stone minimum on DraftKings and could be the ultimate salary saver with Shaheen doubtful.

The Over/Under for this game is currently 39.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Philadelphia Eagles @ New York Jets (+7)

Injury Analysis: Eagles QB Jalen Hurts' status for Week 13 is truly a game time decision due to last week's ankle injury. Hurts says he will be ready to go for the game. If he plays, I believe his mobility will be effected by his ankle. RB Boston Scott has record DNPs all week due to an illness, and it doesn't look good for Week 13. RB Jordan Howard has been ruled out with knee injury.

Fantasy Analysis:  Hurts is out for Week 13, so Gardner Minshew II will get the start. Downgrades for pass-catchers across the board with Philly likely to implement a true ground-and-pound operation. Scott is expected to play but his lack of practice all week makes his workload limited at best. Would avoid starting him if possible and instead be more bullish on Miles Sanders at 5% projected rostership in DFS.

Top streaming options to consider in 1QB leagues with Hurts out include Taylor Heinicke, Tua Tagovailoa, Tyrod Taylor and Jimmy Garoppolo.

The Over/Under for this game is currently 45. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Tampa Bay Buccaneers @ Atlanta Falcons (+10.5)

Injury Analysis: Bucs WR Jaelon Darden has been ruled out with a concussion for Week 13. WR Antonio Brown seems to be healthy enough to play from his ankle injury but will miss the next three games due to violating COVID protocol.

The Over/Under for this game is currently 50.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Arizona Cardinals @ Chicago Bears (+7.5)

Injury Analysis: Cardinals QB Kyler Murray (ankle) and WR DeAndre Hopkins (hamstring) have been given the game time decision tags. I believe they play, as the Cardinals have done a great job managing their injuries.

Bears WR Marquise Goodwin (foot/ribs) and RB Damien Williams (calf) have been ruled out of Week 13. QB Justin Fields (ribs) and Allen Robinson II (hamstring) are both not expected to play this week.

Fantasy Analysis:  Murray's last game action was in Week 8, where he finished as the QB28 after hurting his ankle.

But with so much time off — and DeAndre Hopkins‘s return — fantasy managers shouldn't hesitate to much going back to Murray. Before Murray’s injury, he ranked as the QB4 in fantasy points per game (24.8).

At least these were my initial thoughts on Murray before he and Hopkins were both deemed game-time decisions by head coach Kliff Kingsbury.

Luckily, the schedule gods are working in favor of fantasy football gamers with the Arizona Cardinals–Chicago Bears matchup kicking off at 1 p.m. ET, so you’ll have ample time to make a pivot for a backup plan like Taylor Heinicke, Tyrod Taylor, Jimmy Garoppolo or Tua Tagovailoa.

I wouldn’t play Murray over another waiver wire quarterback if he’s active. Hopkins should be viewed as a fantasy WR2 option. He’s currently WR20 in my fantasy football rankings.

Christian Kirk is the only other Cardinals WR that should be started regardless of Hopkins' status.

The Over/Under for this game is currently 42.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Minnesota Vikings @ Detroit Lions (+7.5)

Injury Analysis: Vikings RB Dalvin Cook and Lions RB D'Andre Swift have been ruled out for Week 13 with shoulder injuries.

Fantasy Analysis: It’s wheels up for Mattison with Dalvin Cook on the shelf for the foreseeable future.

The Vikings' No. 2 running back was a stud when Cook was a sideline for two games earlier in the season, as he averaged 25.7 fantasy points, 25.6 expected fantasy points and 32 touches per game.

He also ran a route on 46% of Kirk Cousins dropbacks — a number that could increase even further. I say that because when Mattison started games earlier in the season, pass-catching specialist Ameer Abdullah was still on the team and running routes out of the backfield

With Abdullah now catching passes out of the backfield in Carolina, we could see Mattison boast even higher route participation, which is why he's No. 3 overall in my running back rankings.

The Over/Under for this game is currently 46.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Indianapolis Colts @ Houston Texans (+10)

Injury Analysis: Texans WR Brandin Cooks and RB David Johnson are both questionable with illnesses. Cooks is trending in the right direction after logging a limited session Friday, but Johnson has yet to see the field this week.

Fantasy Analysis: Don't get cute with Rex Burkhead even if DJ is ruled out. The Texans elevated RB Jaylen Samuels to the active roster. Johnson and  Burkhead have been the main two RBs the last two weeks, and Royce Freeman will be involved for the first time.

It's a RBBC that no fantasy gamer should want any part of.

I'd be more opt to take a DFS flier on Nico Collins with the Texans dealing with injuries to all their WRs.

Collins tied Brandin Cooks with a team-leading five targets last week, two of which came inside the five-yard line. The rookie now has three targets of that variety in his last two games, so I like his chances of hitting paydirt versus the Indianapolis Colts, who rank last in receiving touchdowns to WRs this season.

You could do worse than spending $3.1K on Collins in DraftKings after his target share increased by 10% from Week 11.

The Over/Under for this game is currently 44.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Los Angeles Chargers @ Cincinnati Bengals (-3)

Injury Analysis: Bengals WR Auden Tate (calf), WR Mike Thomas (illness)and RB Chris Evans (ankle) are doubtful, and I do not expect them to play in Week 13.

The Over/Under for this game is currently 49.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Washington Football Team @ Las Vegas Raiders (-1.5)

Injury Analysis: Raiders WR DeSean Jackson is questionable with a calf injury, but I expect him to play. TE Darren Waller logged DNPs all week, and I do not expect him to play in Week 13.

Washington Football Team WR Curtis Samuel is questionable with a groin injury, but I believe he plays this week. TE Ricky Seals-Jones is questionable wit a hip issue, but I expect him to be ready to go. J.D. McKissic has been ruled out with a concussion.

Fantasy Analysis:  Start Foster Moreau. When Moreau started in Darren Waller‘s place in Week 7, he played 100% of Las Vegas' offensive snaps and scored 18 fantasy points. He is an instant fantasy top-12 tight end with out for Week 13.

Play Antonio Gibson. He is the best running back below $6K on DraftKings.

He is mispriced because salaries came out prior to Monday Night Football, where Gibson commanded a career-high seven targets. J.D. McKissic’s concussion bodes well for the second-year running back to finally become a full three-down workhorse who is used in all facets of the offense.

Gibson’s season-long 30th-ranked route participation (36%) has nowhere to go but up, so look for him to erupt versus the Las Vegas Raiders defense that has allowed the fifth-most fantasy points to running backs over the last four weeks.

The Over/Under for this game is currently 49.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Jacksonville Jaguars @ Los Angeles Rams (-13)

Injury Analysis: Rams WR Odell Beckham Jr. injured his hip earlier this week and is questionable for Week 13, but I am optimistic he plays. RB Darrell Henderson Jr. recorded two DNPs and then a limited session. He is trending in the right direction, but I am pessimistic he plays in Week 13.

Jaguars RB James Robinson is questionable with heel/knee issues, but I expect him to be ready to go.

Fantasy Analysis: Lock Sony Michel in DFS lineups if Henderson can't go. In Week 3 with Henderson out, Michel saw a 74% snap share and totaled 23 touches for 79 yards versus the Tampa Bay Buccaneers.

The Over/Under for this game is currently 48. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Baltimore Ravens @ Pittsburgh Steelers (+4.5)

Injury Analysis: N/A

The Over/Under for this game is currently 44. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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San Francisco 49ers @ Seattle Seahawks (+3.5)

Injury Analysis: 49ers WR Deebo Samuel (groin) has been ruled out for Week 13. RB Trey Sermon is battling an ankle injury, and I do not believe he will play this week.

Seahawks RBs Alex Collins, Travis Homer and Rashaad Penny are questionable for Week 13, but I expect them to play.

Fantasy Analysis: The lock-button in cash formats for wide receivers starts with Brandon Aiyuk ($5,600). The second-year wide receiver is making the most of his boost in playing time, as he owns a top-12 route participation mark and a team-leading 23% target share since Week 9.

Fire him up with confidence versus Seattle while Deebo Samuel is sidelined. The Seahawks defense is due for negative regression in terms of passing touchdowns, as it ranks bottom-four in passing yards allowed this season but outside the top half of the league in passing touchdowns allowed.

The Over/Under for this game is currently 45.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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Denver Broncos @ Kansas City Chiefs (-9.5)

Injury Analysis: Chiefs RB Clyde Edwards-Helaire logged a DNP at the end of the week due to an illness, which is never good. He needs to be monitored heading in to Sunday.

Broncos RB Melvin Gordon III is dealing with shoulder/hip injuries. I was surprised he came back into the game after an awkward hip injury. I expect Gordon to be too beat up to play in Week 13.

Fantasy Analysis: Start Javonte Williams as a top-12 running back with Gordon out. 

The rookie has over 100 yards from scrimmage in two of his last three games while working in a timeshare.

Have a backup in place for CEH. Illness can be tricky, so have Darrel Williams, Denver WRs or Patriots WR stashed on your bench in case we get word of Edwards-Helaire's status.

The Over/Under for this game is currently 47. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.

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New England Patriots @ Buffalo Bills (-3)

Injury Analysis: N/A

The Over/Under for this game is currently 41.5. PFF Greenline uses exclusive game and player data to make projections on NFL game spreads, moneyline, and over/under.